Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.60 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.60 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.52 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865792 | 0.90 | CYSLTR1 (0.56) | CYSLTR2CYSLTR1LMNAGPBAR1TP53 | |
| SCHEMBL9876878 | 0.86 | CYSLTR2 (0.52) | CYSLTR2CYSLTR1ADAMTS4GPBAR1CA12 | |
| SCHEMBL9865885 | 0.86 | GPBAR1 (0.57) | CYSLTR2CYSLTR1ADAMTS4GPBAR1PDE10A | |
| SCHEMBL5184799 | 0.81 | AR (0.70) | LMNAHRH3TP53CA12CA1 | |
| SCHEMBL9866064 | 0.81 | GPBAR1 (0.57) | CYSLTR2CYSLTR1GPBAR1PDE10AALOX5 | |
| SCHEMBL9018929 | 0.81 | CYSLTR2 (0.54) | CYSLTR2CYSLTR1ADAMTS4LMNAGPBAR1 | |
| SCHEMBL9866170 | 0.80 | GPBAR1 (0.56) | CYSLTR2CYSLTR1GPBAR1PDE10AALOX5 | |
| SCHEMBL3362235 | 0.80 | CYSLTR1 (0.63) | CYSLTR2CYSLTR1ADAMTS4GPBAR1 | |
| SCHEMBL9508040 | 0.79 | CYSLTR1 (0.60) | CYSLTR2CYSLTR1ADAMTS4ALOX5 | |
| SCHEMBL7008427 | 0.79 | GPBAR1 (0.64) | CYSLTR2CYSLTR1GPBAR1PDE10AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045547-A | Leukotriene-inhibiting substituted (quinolin-2-yl-methoxy)phenyl-N,N'-sulphonylureas and use thereas | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-03 | — | — | US | disclosed |