Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | CYSLTR1 | Q9Y271 | 9/20 | 0.55 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.55 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.52 |
| ▸ | MET | P08581 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866170 | 0.99 | GPBAR1 (0.56) | GPBAR1FFAR1AKR1B1CYSLTR1CYSLTR2 | |
| SCHEMBL9865885 | 0.86 | GPBAR1 (0.57) | GPBAR1FFAR1AKR1B1CYSLTR1CYSLTR2 | |
| SCHEMBL9876648 | 0.81 | CYSLTR2 (0.60) | GPBAR1CYSLTR1CYSLTR2PDE10AALOX5 | |
| SCHEMBL9876878 | 0.81 | CYSLTR2 (0.52) | GPBAR1FFAR1AKR1B1CYSLTR1CYSLTR2 | |
| SCHEMBL7008427 | 0.79 | GPBAR1 (0.64) | GPBAR1FFAR1AKR1B1CYSLTR1CYSLTR2 | |
| SCHEMBL6468349 | 0.78 | PGR (0.62) | MET | |
| SCHEMBL7753530 | 0.77 | CYSLTR1 (0.54) | GPBAR1FFAR1AKR1B1CYSLTR1CYSLTR2 | |
| SCHEMBL9719811 | 0.77 | GPBAR1 (0.62) | GPBAR1FFAR1AKR1B1CYSLTR1CYSLTR2 | |
| SCHEMBL9121462 | 0.77 | CYSLTR1 (0.54) | GPBAR1FFAR1AKR1B1CYSLTR1CYSLTR2 | |
| SCHEMBL9866191 | 0.77 | CYSLTR2 (0.54) | GPBAR1FFAR1AKR1B1CYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045547-A | Leukotriene-inhibiting substituted (quinolin-2-yl-methoxy)phenyl-N,N'-sulphonylureas and use thereas | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-03 | — | — | US | claimed |
| US-5045547-A | Leukotriene-inhibiting substituted (quinolin-2-yl-methoxy)phenyl-N,N'-sulphonylureas and use thereas | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-03 | — | — | US | disclosed |