Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 4/20 | 0.33 |
| ▸ | MMP9 | P14780 | 3/20 | 0.33 |
| ▸ | MMP8 | P22894 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | PGD | P52209 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 3/20 | 0.31 |
| ▸ | MMP3 | P08254 | 2/20 | 0.31 |
| ▸ | MMP7 | P09237 | 2/20 | 0.31 |
| ▸ | MMP20 | O60882 | 1/20 | 0.31 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19233364 | 0.86 | KDM4E (0.46) | KDM4EPDE4ALMNAUSP2MEN1 | |
| SCHEMBL3125161 | 0.86 | KDM4E (0.46) | KDM4EPDE4ALMNAUSP2MEN1 | |
| SCHEMBL13868638 | 0.84 | PDE4A (0.56) | KDM4EPDE4ALMNAUSP2MEN1 | |
| SCHEMBL13359968 | 0.84 | PDE4A (0.56) | KDM4EPDE4ALMNAUSP2MEN1 | |
| SCHEMBL5713241 | 0.84 | PDE4A (0.56) | KDM4EPDE4ALMNAUSP2MEN1 | |
| SCHEMBL14982786 | 0.84 | PDE4A (0.56) | KDM4EPDE4ALMNAUSP2MEN1 | |
| SCHEMBL13572033 | 0.84 | PDE4A (0.56) | KDM4EPDE4ALMNAUSP2MEN1 | |
| SCHEMBL614427 | 0.84 | PDE4A (0.56) | KDM4EPDE4ALMNAUSP2MEN1 | |
| SCHEMBL16349763 | 0.84 | PDE4A (0.56) | KDM4EPDE4ALMNAUSP2MEN1 | |
| Water SCHEMBL28832904 | 0.82 | PDE4A (0.54) | KDM4EPDE4ALMNAUSP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071871-A | Pharmaceutically useful benzo(β)pyranes and pyranopyridines | SANDOZ LTD. (CH) | 1991-12-10 | — | — | US | disclosed |