Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 1/20 | 0.38 |
| ▸ | CCNH | P51946 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9235184 | 0.93 | NTRK1 (0.38) | CDK1CDK4CCNB1CCNA2CCND1 | |
| Fumaric Acid SCHEMBL9235180 | 0.93 | NTRK1 (0.38) | CDK1CDK4CCNB1CCNA2CCND1 | |
| SCHEMBL9877014 | 0.91 | PTGER1 (0.41) | CCNA2CDK2NTRK1FABP4PTGER1 | |
| SCHEMBL9231716 | 0.91 | CCNA2 (0.38) | CCNA2CDK2NTRK1GAAPOLB | |
| SCHEMBL9876945 | 0.88 | CCNA2 (0.37) | CDK1CDK4CCNB1CCNA2CCND1 | |
| Maleic Acid SCHEMBL9235054 | 0.85 | PTGER1 (0.41) | CCNA2CDK2NTRK1FABP4PTGER1 | |
| Fumaric Acid SCHEMBL9235061 | 0.85 | PTGER1 (0.41) | CCNA2CDK2NTRK1FABP4PTGER1 | |
| Fumaric Acid SCHEMBL10591489 | 0.84 | NPSR1 (0.39) | CCNA2CDK2NTRK1GAAPOLB | |
| Fumaric Acid SCHEMBL10591480 | 0.84 | NPSR1 (0.39) | CCNA2CDK2NTRK1GAAPOLB | |
| SCHEMBL9877691 | 0.84 | CCNA2 (0.39) | CDK1CDK4CCNB1CCNA2CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |