Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9235061 | 0.94 | PTGER1 (0.41) | PTGER1GBA1CCNA2CDK2MCHR1 | |
| Maleic Acid SCHEMBL9235054 | 0.94 | PTGER1 (0.41) | PTGER1GBA1CCNA2CDK2MCHR1 | |
| SCHEMBL9231716 | 0.91 | CCNA2 (0.38) | PTGER1CCNA2CDK2NTRK1PDE4A | |
| SCHEMBL9876728 | 0.91 | CDK1 (0.38) | PTGER1CCNA2CDK2NTRK1PDE4A | |
| SCHEMBL9876520 | 0.87 | PTGER1 (0.38) | PTGER1GBA1CCNA2CDK2PDE4A | |
| Fumaric Acid SCHEMBL9235180 | 0.87 | NTRK1 (0.38) | PTGER1CCNA2CDK2NTRK1PDE4A | |
| Fumaric Acid SCHEMBL9235184 | 0.87 | NTRK1 (0.38) | PTGER1CCNA2CDK2NTRK1PDE4A | |
| Fumaric Acid SCHEMBL10591480 | 0.87 | NPSR1 (0.39) | PTGER1CCNA2CDK2NTRK1TP53 | |
| Fumaric Acid SCHEMBL10591489 | 0.87 | NPSR1 (0.39) | PTGER1CCNA2CDK2NTRK1TP53 | |
| Maleic Acid SCHEMBL9237812 | 0.83 | PTGER1 (0.40) | PTGER1CCNA2CDK2PDE4AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |