Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | RGS12 | O14924 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 2/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4146720 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPTPOLBTDP1RECQL | |
| SCHEMBL31718394 | 0.76 | KDM1A (0.47) | ALDH1A1MAPTPOLBTDP1RECQL | |
| SCHEMBL20830555 | 0.76 | MAPT (0.44) | ALDH1A1MAPTPOLBTDP1RECQL | |
| SCHEMBL6568199 | 0.76 | KDM1A (0.47) | ALDH1A1MAPTPOLBTDP1RECQL | |
| SCHEMBL1072174 | 0.72 | ALDH1A1 (0.42) | ALDH1A1MAPTPOLBTDP1RECQL | |
| SCHEMBL29728715 | 0.72 | ALDH1A1 (0.42) | ALDH1A1MAPTPOLBTDP1RECQL | |
| SCHEMBL27647094 | 0.72 | MAPT (0.41) | ALDH1A1MAPTPOLBTDP1RECQL | |
| SCHEMBL17850566 | 0.72 | MAPT (0.41) | ALDH1A1MAPTPOLBTDP1RECQL | |
| SCHEMBL24505979 | 0.72 | MAPT (0.38) | ALDH1A1MAPTPOLBTDP1RECQL | |
| SCHEMBL673129 | 0.71 | ALDH1A1 (0.41) | ALDH1A1MAPTPOLBTDP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001171-A | Process, modified rubbers and rubber compositions | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0319733-A2 | Process, modified rubbers and rubber compositions | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1989-06-14 | — | — | EP | disclosed |
| US-4788229-A | BLENDING MIXTURES OF UNCURED ELASTOMERS AND FILLERS CONTAINING ELASTOMER-FILLER LINKAGE PROMOTERS; TIRES; FRICTION RESISTANCE; REDUCED HYSTERESIS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1988-11-29 | — | — | US | disclosed |