Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL988515 | 0.92 | PTGDR2 (0.47) | PTGDR2PDE4DCA12CA1CA2 | |
| SCHEMBL2769871 | 0.91 | PTGDR2 (0.58) | PTGDR2CA12CA1CA2CA4 | |
| SCHEMBL2772208 | 0.86 | PTGDR2 (0.62) | PTGDR2CA12CA1CA2CA4 | |
| SCHEMBL2771309 | 0.85 | PTGDR2 (0.57) | PTGDR2CA12CA1CA2CA4 | |
| SCHEMBL2773959 | 0.85 | PTGDR2 (0.66) | PTGDR2CA12CA1CA2CA4 | |
| SCHEMBL2770545 | 0.84 | PTGDR2 (0.58) | PTGDR2CA12CA1CA2CA4 | |
| SCHEMBL2771985 | 0.84 | PTGDR2 (0.62) | PTGDR2CA12CA1CA2CA4 | |
| SCHEMBL2771665 | 0.84 | PTGDR2 (0.58) | PTGDR2CA12CA1CA2CA4 | |
| SCHEMBL2773279 | 0.84 | PTGDR2 (0.58) | PTGDR2CA12CA1CA2CA4 | |
| SCHEMBL2773541 | 0.84 | PTGDR2 (0.58) | PTGDR2CA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010102154-A2 | BIARYL OXYACETIC ACID COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-09-10 | — | — | WO | claimed |
| WO-2011002814-A2 | BIARYL OXYACETIC ACID COMPOUNDS | LIGAND PHARMACEUTICALS INC. (US) | 2011-01-06 | — | — | WO | disclosed |
| WO-2010102154-A2 | BIARYL OXYACETIC ACID COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-09-10 | — | — | WO | disclosed |