Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 6/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3262446 | 0.74 | MPO (0.57) | MPOKDM4ETSHRCYP2D6HIF1A | |
| Acetic Acid SCHEMBL28061900 | 0.66 | AKR1B1 (0.50) | MPOKDM4ETSHRCYP2D6HIF1A | |
| SCHEMBL8050377 | 0.66 | CYP11B1 (0.65) | KDM4ECYP2D6 | |
| Hydrochloric Acid SCHEMBL4419226 | 0.65 | PON1 (0.54) | — | |
| Bromide SCHEMBL10941970 | 0.64 | CYP11B1 (0.63) | KDM4ECYP2D6 | |
| SCHEMBL3967782 | 0.62 | MPO (1.00) | MPOKDM4ETSHRCYP2D6HIF1A | |
| SCHEMBL20527465 | 0.61 | CYP11B1 (0.50) | KDM4E | |
| SCHEMBL1488764 | 0.60 | TSHR (0.67) | MPOKDM4ETSHRCYP2D6HIF1A | |
| SCHEMBL10917974 | 0.60 | BRD4 (0.56) | MPOKDM4ETSHRCYP2D6HIF1A | |
| SCHEMBL10415354 | 0.60 | MPO (0.84) | MPOKDM4ETSHRHIF1ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001171-A | Process, modified rubbers and rubber compositions | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-03-19 | — | — | US | claimed |
| US-4788229-A | BLENDING MIXTURES OF UNCURED ELASTOMERS AND FILLERS CONTAINING ELASTOMER-FILLER LINKAGE PROMOTERS; TIRES; FRICTION RESISTANCE; REDUCED HYSTERESIS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1988-11-29 | — | — | US | claimed |