Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6397529 | 0.87 | DPP8 (0.54) | TGM2DPP8DPP9ALDH1A1MAPT | |
| SCHEMBL6397257 | 0.80 | DPP8 (0.57) | TGM2DPP8DPP9ALDH1A1MAPT | |
| SCHEMBL27388024 | 0.79 | IDO1 (0.51) | DPP8DPP9ALDH1A1MAPTRAB9A | |
| SCHEMBL8439536 | 0.79 | HTT (0.50) | ALDH1A1MAPTRAB9AGAAIDO1 | |
| SCHEMBL10500161 | 0.79 | DPP8 (0.58) | TGM2DPP8DPP9ALDH1A1MAPT | |
| SCHEMBL10756101 | 0.79 | DPP8 (0.59) | TGM2DPP8DPP9ALDH1A1MAPT | |
| SCHEMBL27536768 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MAPTRAB9AGAAHTT | |
| SCHEMBL2299040 | 0.77 | IDO1 (0.58) | ALDH1A1MAPTRAB9AGAAIDO1 | |
| SCHEMBL11165857 | 0.76 | IDO1 (0.53) | ALDH1A1MAPTRAB9AIDO1AKR1C3 | |
| SCHEMBL11161416 | 0.75 | DPP8 (0.55) | TGM2DPP8DPP9ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992542-A | Thienamycin antibiotics | MERCK & CO., INC. (US) | 1991-02-12 | — | — | US | disclosed |