Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 12/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 10/20 | 0.53 |
| ▸ | PARP15 | Q460N3 | 5/20 | 0.51 |
| ▸ | PARP14 | Q460N5 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL8359782 | 0.85 | SLC7A5 (0.54) | PARP1PARP10PARP15PARP14POLB | |
| SCHEMBL2850002 | 0.83 | MEN1 (0.67) | PARP1PARP10PARP15PARP14MEN1 | |
| SCHEMBL12545738 | 0.76 | PARP1 (0.60) | PARP1PARP10PARP15PARP14MEN1 | |
| SCHEMBL30668647 | 0.76 | PARP1 (0.60) | PARP1PARP10PARP15PARP14MEN1 | |
| SCHEMBL4795890 | 0.75 | KMT2A (0.66) | MEN1KMT2APOLBMAPTNPC1 | |
| SCHEMBL4893340 | 0.75 | PARP1 (0.66) | PARP1PARP10PARP15PARP14MEN1 | |
| SCHEMBL5210059 | 0.75 | KMT2A (0.62) | MEN1KMT2ACASRMAPTGAA | |
| SCHEMBL27999432 | 0.75 | PARP1 (0.50) | PARP1PARP10PARP15PARP14MEN1 | |
| SCHEMBL895009 | 0.74 | PARP1 (0.63) | PARP1PARP10PARP15PARP14MEN1 | |
| Urea SCHEMBL307661 | 0.74 | KMT2A (0.60) | MEN1KMT2ACASRMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017211-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1991-05-21 | — | — | US | disclosed |
| EP-0333791-A1 | HETEROCYCLIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1989-09-27 | — | — | EP | disclosed |
| WO-1989002891-A1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1989-04-06 | — | — | WO | disclosed |