Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | PARP1 | P09874 | 16/20 | 0.63 |
| ▸ | PARP10 | Q53GL7 | 12/20 | 0.63 |
| ▸ | PARP15 | Q460N3 | 7/20 | 0.63 |
| ▸ | PARP14 | Q460N5 | 4/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5425792 | 0.86 | MEN1 (0.65) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL5210059 | 0.86 | KMT2A (0.62) | MEN1KMT2A | |
| SCHEMBL4795890 | 0.86 | KMT2A (0.66) | MEN1KMT2A | |
| SCHEMBL28280295 | 0.86 | MEN1 (0.65) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL4893340 | 0.86 | PARP1 (0.66) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL3690365 | 0.85 | MAPT (0.59) | MEN1KMT2A | |
| SCHEMBL408480 | 0.85 | PARP1 (0.63) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL895690 | 0.85 | MEN1 (0.63) | MEN1KMT2APARP1PARP10PARP15 | |
| Urea SCHEMBL307661 | 0.85 | KMT2A (0.60) | MEN1KMT2A | |
| SCHEMBL4531507 | 0.85 | ALDH1A1 (0.71) | MEN1KMT2APARP1PARP10PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| US-20190196073-A1 | COMPOSITION, FILM, NEAR INFRARED CUT FILTER, PATTERN FORMING METHOD, LAMINATE, SOLID IMAGE PICKUP ELEMENT, IMAGE DISPLAY DEVICE, CAMERA MODULE, AND INFRARED SENSOR | FUJIFILM CORPORATION (JP) | 2019-06-27 | — | — | US | disclosed |
| WO-2017030859-A1 | CCK2R-DRUG CONJUGATES | ENDOCYTE, INC. (US) | 2017-02-23 | — | — | WO | disclosed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |
| US-20080064690-A1 | PYRAZOLE-AMIDES AND -SULFONAMIDES | ICAGEN, INC. (US) | 2008-03-13 | — | — | US | disclosed |
| US-7223782-B2 | Pyrazole-amides and -sulfonamides | ICAGEN, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-20050049237-A1 | Pyrazole-amides and -sulfonamides | ICAGEN, INC. (US) | 2005-03-03 | — | — | US | disclosed |
| CN-1051079-C | Benzodiazepine * derivatives, process for their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMA CO LTD (JP) | 2000-04-05 | — | — | CN | disclosed |
| US-5719151-A | PHTHALAZINEDIONE COMPOUND; POLYMERASE INHIBITOR | SHALL SYDNEY (GB) | 1998-02-17 | — | — | US | disclosed |
| CN-1075717-A | Benzodiazepine * derivatives | YAMANOUCHI PHARMA CO LTD (JP) | 1993-09-01 | — | — | CN | disclosed |
| US-5017211-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1991-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064690-A1 | PYRAZOLE-AMIDES AND -SULFONAMIDES | SCN3A, TRPV3, HCN3 | MEN1 4543/4885KMT2A 2659/4885PARP1 3600/4885 |
| US-20050049237-A1 | Pyrazole-amides and -sulfonamides | SCN3A, TRPV3, HCN3 | MEN1 4543/4885KMT2A 2659/4885PARP1 3600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.