Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 12/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9878305 | 0.89 | MEN1 (0.53) | TP53TSHRMTNR1AMTNR1BMEN1 | |
| SCHEMBL9772333 | 0.86 | TSHR (0.48) | TP53TSHRMTNR1AMTNR1BMEN1 | |
| SCHEMBL9402006 | 0.81 | KDM4E (0.59) | TP53TSHRMTNR1AMTNR1BMEN1 | |
| SCHEMBL10555016 | 0.81 | TP53 (0.43) | TP53TSHRMTNR1AMTNR1BMEN1 | |
| SCHEMBL10550322 | 0.79 | KDM4E (0.43) | TP53TSHRMTNR1AMEN1KMT2A | |
| SCHEMBL13413716 | 0.79 | MEN1 (0.52) | TP53TSHRMTNR1AMTNR1BMEN1 | |
| SCHEMBL10553702 | 0.72 | HTT (0.52) | TSHRKMT2A | |
| SCHEMBL9877462 | 0.70 | KDM4E (0.39) | TP53TSHRMEN1KMT2AMAPT | |
| SCHEMBL9772274 | 0.70 | KDM4E (0.49) | TP53MTNR1AMTNR1BMAPTKDM4E | |
| SCHEMBL11311391 | 0.70 | LMNA (0.42) | TP53TSHRMTNR1AMTNR1BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213326-B1 | 2,5-DIMETHYL PYRROLE DERIVATIVES, THEIR PREPARATION AND THEIR USE | CASSELLA Aktiengesellschaft (DE) | 1991-03-06 | — | — | EP | disclosed |
| US-4837225-A | ENCEPHALOTROPIC AND PSYCHOTROPIC EFFECTS | CASSELL AKTIENGESELLSCHAFT (DE) | 1989-06-06 | — | — | US | disclosed |