Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.30 |
| ▸ | CTRC | Q99895 | 2/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877871 | 1.00 | PRSS1 (0.30) | PRSS1CTRCF2 | |
| SCHEMBL9875593 | 0.89 | — | — | |
| SCHEMBL9874215 | 0.89 | — | — | |
| SCHEMBL9875863 | 0.89 | — | — | |
| SCHEMBL24586795 | 0.64 | PRSS1 (0.38) | PRSS1CTRCF2 | |
| SCHEMBL7776997 | 0.64 | PRSS1 (0.38) | PRSS1CTRCF2 | |
| SCHEMBL7776998 | 0.64 | PRSS1 (0.38) | PRSS1CTRCF2 | |
| SCHEMBL16269062 | 0.61 | ESR2 (0.31) | — | |
| SCHEMBL6688256 | 0.59 | ESR2 (0.36) | — | |
| SCHEMBL14954535 | 0.58 | NOS1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043451-A | Bicyclo (2.2.1.) hept-exo-2-yl and bicyclo (2.2.2.) oct-endo-2-yl compounds | SHIONOGI & CO., LTD. (JP) | 1991-08-27 | — | — | US | disclosed |
| US-5041635-A | 5(Z)-7-(endo-3-benzenesulfonamidobicyclo[2.2.1]hept-exo-2-yl)-5-heptenoic acid, sodium salt | SHIONOGI & CO., LTD. (JP) | 1991-08-20 | — | — | US | disclosed |
| EP-0226346-B1 | BICYCLIC SULFONAMIDE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4976891-A | Antithrombotic, antivasoconstricting, antibronchoconstricting | SHIONOGI & CO., LTD. (JP) | 1990-12-11 | — | — | US | disclosed |
| US-4960909-A | ANTICOAGULANTS; VASODILATORS; BRONCHODILATOR AGENTS | SHIONOGI & CO., LTD. (JP) | 1990-10-02 | — | — | US | disclosed |
| US-4861913-A | Bicyclic sulfonamide derivatives | SHIONOGI & CO., LTD. (JP) | 1989-08-29 | — | — | US | disclosed |
| EP-0226346-A1 | Bicyclic sulfonamide derivatives | SHIONOGI & CO., LTD. (JP) | 1987-06-24 | — | — | EP | disclosed |