Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 5/20 | 0.39 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9878292 | 1.00 | MAPT (0.44) | MAPTTHRBSMN1; SMN2ADRB2ADRB1 | |
| SCHEMBL9878776 | 0.89 | MAPT (0.47) | MAPTTHRBSMN1; SMN2NPC1TP53 | |
| SCHEMBL9878773 | 0.89 | MAPT (0.47) | MAPTTHRBSMN1; SMN2NPC1TP53 | |
| SCHEMBL12225731 | 0.89 | PPARD (0.47) | MAPTTHRBSMN1; SMN2ADRB2ADRB1 | |
| SCHEMBL9878245 | 0.89 | PPARD (0.47) | MAPTTHRBSMN1; SMN2ADRB2ADRB1 | |
| SCHEMBL9878246 | 0.89 | PPARD (0.47) | MAPTTHRBSMN1; SMN2ADRB2ADRB1 | |
| SCHEMBL9878481 | 0.89 | ALDH1A1 (0.47) | MAPTTHRBSMN1; SMN2NPC1TP53 | |
| SCHEMBL9878486 | 0.89 | ALDH1A1 (0.47) | MAPTTHRBSMN1; SMN2NPC1TP53 | |
| SCHEMBL9879147 | 0.88 | MAPT (0.45) | MAPTTHRBSMN1; SMN2NPC1POLB | |
| SCHEMBL9879143 | 0.88 | MAPT (0.45) | MAPTTHRBSMN1; SMN2NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013476-A | Ferroelectric properties, electro-optical indicating device | HOFFMANN-LA ROCHE INC. (US) | 1991-05-07 | — | — | US | disclosed |