Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | GRN | P28799 | 4/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.40 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438839 | 0.82 | ERCC5 (0.57) | GPR139ALDH1A1P2RX7MEN1HPGD | |
| SCHEMBL3786992 | 0.81 | GSK3B (0.53) | RAB9AALDH1A1MAPTPOLBCNR1 | |
| SCHEMBL12788976 | 0.78 | TPMT (0.48) | RAB9ATPMTFABP4GRNSORT1 | |
| SCHEMBL10614980 | 0.77 | TPMT (0.43) | RAB9ATPMTFABP4GRNSORT1 | |
| SCHEMBL28128775 | 0.76 | GRN (0.43) | RAB9ATPMTFABP4GRNSORT1 | |
| SCHEMBL10480836 | 0.74 | KDM4E (0.56) | MAPTMTNR1AMTNR1BSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28267005 | 0.74 | GRN (0.42) | RAB9ATPMTFABP4GRNSORT1 | |
| SCHEMBL23014293 | 0.73 | MEN1 (0.52) | RAB9AFABP4GPR139ALDH1A1MAPT | |
| SCHEMBL633305 | 0.73 | TPMT (0.52) | RAB9ATPMTFABP4GRNSORT1 | |
| SCHEMBL4068730 | 0.72 | TACR1 (0.50) | RAB9AALDH1A1MAPTPOLBP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991002730-A1 | NEW SUBSTITUTED FIVE-MEMBERED HETEROCYCLIC RINGS, THEIR PREPARATION AND THEIR USE | BOEHRINGER INGELHEIM KG (DE) | 1991-03-07 | — | — | WO | disclosed |