SCHEMBL9879113

SCHEMBL9879113

Cc1ccccc1Nc1nc(CO)cc(N(C)c2ccccc2)n1

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9879076 0.88 NPC1 (0.41) NPC1RAB9A
SCHEMBL2407403 0.87 MCHR1 (0.43) NPC1RAB9A
Hydrochloric Acid SCHEMBL9879428 0.86 MEN1 (0.44)
SCHEMBL9878760 0.86
Hydrochloric Acid SCHEMBL9878934 0.86 MCHR1 (0.43) NPC1RAB9A
SCHEMBL9879397 0.86 MEN1 (0.53) NPC1RAB9A
Hydrochloric Acid SCHEMBL9878699 0.85
Hydrochloric Acid SCHEMBL9878646 0.82 TAAR1 (0.52) NPC1RAB9A
Hydrochloric Acid SCHEMBL9878207 0.82 MCHR1 (0.38)
SCHEMBL2410437 0.81 NPC1 (0.48) NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991018887-A1 DIAMINOPYRIMIDINE COMPOUNDS SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) 1991-12-12 WO disclosed