Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879113 | 0.86 | NPC1 (0.41) | NPC1RAB9A | |
| SCHEMBL9879076 | 0.86 | NPC1 (0.41) | NPC1RAB9A | |
| SCHEMBL2407403 | 0.85 | MCHR1 (0.43) | NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9879428 | 0.84 | MEN1 (0.44) | MEN1KMT2A | |
| SCHEMBL9878760 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL9878934 | 0.84 | MCHR1 (0.43) | NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9878699 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL9878646 | 0.80 | TAAR1 (0.52) | NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9878207 | 0.80 | MCHR1 (0.38) | — | |
| SCHEMBL2410437 | 0.79 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018887-A1 | DIAMINOPYRIMIDINE COMPOUNDS | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1991-12-12 | — | — | WO | disclosed |