Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 17/20 | 0.65 |
| ▸ | PTGDR | Q13258 | 15/20 | 0.65 |
| ▸ | PDE2A | O00408 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518655 | 0.93 | TBXA2R (0.57) | TBXA2RPTGDRHDAC2HDAC8HDAC6 | |
| SCHEMBL10517481 | 0.89 | TBXA2R (0.62) | TBXA2RPTGDRPDE2AHDAC2HDAC8 | |
| SCHEMBL10769971 | 0.87 | TBXA2R (0.53) | TBXA2RPTGDR | |
| SCHEMBL10588990 | 0.86 | TBXA2R (0.67) | TBXA2RPTGDRPDE2A | |
| SCHEMBL10585888 | 0.86 | TBXA2R (0.52) | TBXA2RPTGDRPDE2A | |
| SCHEMBL9879388 | 0.81 | TBXA2R (0.58) | TBXA2RPTGDRPDE2A | |
| SCHEMBL10582670 | 0.80 | TBXA2R (0.63) | TBXA2RPTGDRPDE2AHDAC2HDAC8 | |
| SCHEMBL9521310 | 0.79 | TBXA2R (0.64) | TBXA2RPTGDRPDE2AHDAC2HDAC8 | |
| SCHEMBL9521476 | 0.79 | TBXA2R (1.00) | TBXA2RPTGDRPDE2A | |
| SCHEMBL6268039 | 0.78 | TBXA2R (0.75) | TBXA2RPTGDRPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234708-B1 | TETRAHYDROCARBAZOLE 1-ALKANOIC ACIDS | MERCK FROSST CANADA INC. (CA) | 1991-02-27 | — | — | EP | claimed |