Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 14/20 | 0.58 |
| ▸ | TBXAS1 | P24557 | 8/20 | 0.51 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10588990 | 0.91 | TBXA2R (0.67) | TBXA2RTBXAS1PDE2APTGDR | |
| SCHEMBL9518655 | 0.88 | TBXA2R (0.57) | TBXA2RPTGDR | |
| SCHEMBL9518853 | 0.81 | TBXA2R (0.85) | TBXA2RTBXAS1PDE2APTGDR | |
| SCHEMBL9879273 | 0.81 | TBXA2R (0.65) | TBXA2RPDE2APTGDR | |
| SCHEMBL9519669 | 0.81 | TBXA2R (0.56) | TBXA2RTBXAS1PDE2AAKR1B10AKR1A1 | |
| SCHEMBL10769971 | 0.80 | TBXA2R (0.53) | TBXA2RPTGDR | |
| SCHEMBL9518380 | 0.79 | TBXA2R (0.67) | TBXA2RTBXAS1PDE2APTGDRPTGDR2 | |
| SCHEMBL9878840 | 0.79 | TBXA2R (0.41) | TBXA2RTBXAS1PTGDRPTGDR2 | |
| SCHEMBL10585888 | 0.76 | TBXA2R (0.52) | TBXA2RPDE2APTGDR | |
| SCHEMBL9518789 | 0.75 | TBXA2R (0.69) | TBXA2RTBXAS1PDE2AAKR1B1PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234708-B1 | TETRAHYDROCARBAZOLE 1-ALKANOIC ACIDS | MERCK FROSST CANADA INC. (CA) | 1991-02-27 | — | — | EP | claimed |
| EP-0234708-B1 | TETRAHYDROCARBAZOLE 1-ALKANOIC ACIDS | MERCK FROSST CANADA INC. (CA) | 1991-02-27 | — | — | EP | disclosed |