Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21388355 | 0.71 | MAPK10 (0.36) | KDM4EMEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL31185646 | 0.70 | TRPM4 (0.56) | TRPM4NQO2KDM4EMEN1MAPT | |
| SCHEMBL1857725 | 0.70 | MAPK10 (0.35) | KDM4EMEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL723505 | 0.68 | TRPM4 (0.54) | TRPM4NQO2KDM4EMEN1LMNA | |
| SCHEMBL12809944 | 0.67 | TRPM4 (0.37) | TRPM4NQO2KDM4EATMMEN1 | |
| SCHEMBL12809939 | 0.67 | TRPM4 (0.37) | TRPM4NQO2KDM4EATMMEN1 | |
| SCHEMBL29372877 | 0.67 | TRPM4 (0.52) | TRPM4NQO2KDM4EMEN1LMNA | |
| SCHEMBL27986123 | 0.67 | TRPM4 (0.47) | TRPM4NQO2KDM4EMEN1LMNA | |
| SCHEMBL6544568 | 0.66 | ERN1 (0.63) | TRPM4NQO2KDM4EERN1MEN1 | |
| SCHEMBL7752270 | 0.66 | ACHE (0.53) | KDM4EMAPTHTTSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5053150-A | Dispersant; oil or fuel additive | EXXON CHEMICAL PATENTS INC. (US) | 1991-10-01 | — | — | US | disclosed |
| EP-0304175-A1 | Lactone-modified, Mannich base dispersant additives useful in oleaginous compositions | EXXON CHEMICAL PATENTS INC. (US) | 1989-02-22 | — | — | EP | disclosed |