Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP known ✓ | O00591 | 1/20 | 0.58 |
| ▸ | GABRD known ✓ | O14764 | 1/20 | 0.58 |
| ▸ | GABRA1 known ✓ | P14867 | 1/20 | 0.58 |
| ▸ | GABRB1 known ✓ | P18505 | 1/20 | 0.58 |
| ▸ | GABRG2 known ✓ | P18507 | 1/20 | 0.58 |
| ▸ | GABRB3 known ✓ | P28472 | 1/20 | 0.58 |
| ▸ | GABRA5 known ✓ | P31644 | 1/20 | 0.58 |
| ▸ | GABRA3 known ✓ | P34903 | 1/20 | 0.58 |
| ▸ | GABRA2 known ✓ | P47869 | 1/20 | 0.58 |
| ▸ | GABRB2 known ✓ | P47870 | 1/20 | 0.58 |
| ▸ | GABRA4 known ✓ | P48169 | 1/20 | 0.58 |
| ▸ | GABRE known ✓ | P78334 | 1/20 | 0.58 |
| ▸ | GABRA6 known ✓ | Q16445 | 1/20 | 0.58 |
| ▸ | GABRG1 known ✓ | Q8N1C3 | 1/20 | 0.58 |
| ▸ | GABRG3 known ✓ | Q99928 | 1/20 | 0.58 |
| ▸ | GABRQ known ✓ | Q9UN88 | 1/20 | 0.58 |
| ▸ | ACE known ✓ | P12821 | 1/20 | 0.42 |
| ▸ | SLC6A1 known ✓ | P30531 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopropane Carboxylic Acid SCHEMBL37200 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL9540139 | 1.00 | TSHR (0.58) | TSHRGABRPGABRDGABRA1GABRB1 | |
| Cyclopropane Carboxylic Acid SCHEMBL31174891 | 1.00 | TSHR (0.58) | TSHRGABRPGABRDGABRA1GABRB1 | |
| Hydrochloric Acid SCHEMBL2060062 | 1.00 | TSHR (0.58) | TSHRGABRPGABRDGABRA1GABRB1 | |
| Hydrochloric Acid SCHEMBL1060402 | 1.00 | TSHR (0.58) | TSHRGABRPGABRDGABRA1GABRB1 | |
| Cyclopropane Carboxylic Acid SCHEMBL15821707 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL2060066 | 1.00 | TSHR (0.58) | TSHRGABRPGABRDGABRA1GABRB1 | |
| Cyclopropane Carboxylic Acid SCHEMBL5499291 | 0.96 | — | — | |
| SCHEMBL26833 | 0.96 | TSHR (0.61) | TSHRGABRPGABRDGABRA1GABRB1 | |
| Cyclopropane Carboxylic Acid SCHEMBL4643 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118142347-A | Preparation method of aliphatic positive nanofiltration membrane based on polyamine diacid chloride monomer | 中国石油大学(华东) | 2024-06-07 | — | — | CN | claimed |
| CN-115850117-B | Method for preparing 1, 4-cyclohexane diisocyanate | 黎明化工研究设计院有限责任公司 | 2024-06-04 | — | — | CN | claimed |
| CN-118085274-A | Polyamide precoating resin, preparation method thereof and polyamide resin coating | 浙江鹏孚隆科技股份有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-117946391-A | Micro-crosslinking polyimide resin, polyimide film and preparation method thereof | 华为技术有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-117946392-A | Terminal group crosslinked polyimide resin, polyimide film and preparation method thereof | 华为技术有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-117844392-A | OCA (optical adhesive tape adhesive) with high-adhesion and low-adhesion multilayer structure for optical bonding and preparation method thereof | 睿合科技有限公司 | 2024-04-09 | — | — | CN | claimed |
| WO-2023231317-A1 | NANOFILTRATION MEMBRANE PREPARATION METHOD AND NANOFILTRATION MEMBRANE PREPARED THEREBY | 沃顿科技股份有限公司 | 2023-12-07 | — | — | WO | claimed |
| CN-116769161-A | Polyimide with low CTE and high light transmittance, diamine monomer thereof and preparation method thereof | 河北科技大学 | 2023-09-19 | — | — | CN | claimed |
| CN-112062949-B | Semi-aromatic polyamino acid, semi-aromatic polyamino acid-based bone repair material and preparation thereof | 中鼎凯瑞科技成都有限公司 | 2023-04-25 | — | — | CN | claimed |
| CN-112717721-B | Acid-resistant composite nanofiltration membrane and preparation method thereof | 湖南澳维科技股份有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-113856488-A | Composite nanofiltration membrane and preparation method thereof | 湖南澳维环保科技有限公司 | 2021-12-31 | — | — | CN | claimed |
| CN-110408584-B | Left-handed chiral nanogel cell scaffold material and preparation method thereof | 上海交通大学 | 2021-09-07 | — | — | CN | claimed |
| CN-112870989-A | Anti-pollution composite reverse osmosis membrane and preparation method thereof | 中化(宁波)润沃膜科技有限公司 | 2021-06-01 | — | — | CN | claimed |
| CN-107428672-B | Mixture of polymerizable compounds and method for producing same | 日本瑞翁株式会社 | 2021-05-14 | — | — | CN | claimed |
| CN-112717717-A | Polysulfone-based membrane, reverse osmosis composite membrane containing same and preparation method | 中化(宁波)润沃膜科技有限公司 | 2021-04-30 | — | — | CN | claimed |
| CN-112717721-A | Acid-resistant composite nanofiltration membrane and preparation method thereof | 湖南澳维环保科技有限公司 | 2021-04-30 | — | — | CN | claimed |
| CN-112062949-A | Semi-aromatic polyamino acid, semi-aromatic polyamino acid-based bone repair material and preparation thereof | 中鼎凯瑞科技成都有限公司 | 2020-12-11 | — | — | CN | claimed |
| CN-107151204-B | Method for producing 1, 4-cyclohexanedicarboxylic acid chloride | 东丽精细化工株式会社 | 2020-10-23 | — | — | CN | claimed |
| CN-108079806-B | Polyamide semipermeable membrane, preparation method and application thereof | 浙江大学 | 2020-09-08 | — | — | CN | claimed |
| CN-108291999-B | Optical film, polarizing plate, image display device, polymerizable compound, and method for producing 1, 4-cyclohexanedicarboxylic acid monoaryl ester | 富士胶片株式会社 | 2020-07-10 | — | — | CN | claimed |