Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 5/20 | 0.54 |
| ▸ | TTR | P02766 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10586560 | 0.94 | TTR (0.51) | SRD5A2TTRHPGDCYP1A2CYP2D6 | |
| SCHEMBL10148365 | 0.88 | TTR (0.69) | SRD5A2TTRALDH1A1POLBGAA | |
| SCHEMBL11305006 | 0.87 | TTR (0.54) | TTRHPGDCYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9316831 | 0.85 | TTR (0.53) | SRD5A2TTRCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL27481396 | 0.85 | PARP10 (0.59) | TTRALDH1A1SMN1; SMN2LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL27497210 | 0.84 | PARP10 (0.57) | TTRALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL8070206 | 0.84 | TTR (0.55) | TTRHPGDALDH1A1KMT2AGAA | |
| SCHEMBL24469100 | 0.81 | ALDH1A1 (0.60) | HPGDCYP1A2CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL12531441 | 0.81 | ALDH1A1 (0.60) | HPGDCYP1A2CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL13745810 | 0.81 | ALDH1A1 (0.60) | HPGDCYP1A2CYP2C19ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990589-A | Engineering thermoplastic resin | RAYCHEM LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |
| EP-0315441-A2 | Poly(arylene ether ketones) | RAYCHEM LIMITED (GB) | 1989-05-10 | — | — | EP | disclosed |