Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909676 | 0.79 | THRB (0.41) | AKT1THRBTGM2NSD2MAPT | |
| SCHEMBL7759624 | 0.77 | AKT1 (0.48) | AKT1THRBTGM2MAPTKMT2A | |
| SCHEMBL8693299 | 0.76 | AKT1 (0.46) | AKT1TGM2MAPTKMT2ATDP1 | |
| SCHEMBL11869920 | 0.75 | AKT1 (0.42) | AKT1ELANETHRBTGM2PARP10 | |
| SCHEMBL9420999 | 0.75 | THRB (0.41) | AKT1THRBTGM2NSD2MAPT | |
| Acrylic Acid SCHEMBL29289447 | 0.74 | KMT2A (0.58) | AKT1PARP10NSD2MAPTKMT2A | |
| Benzoic Acid SCHEMBL29757227 | 0.74 | DAO (0.54) | AKT1ELANETHRBTGM2MAPT | |
| Hydrogen Peroxide SCHEMBL28479331 | 0.73 | THRB (0.58) | AKT1THRBTGM2NSD2MAPT | |
| SCHEMBL10938879 | 0.73 | THRB (0.40) | AKT1ELANETHRBTGM2NSD2 | |
| SCHEMBL28916 | 0.73 | THRB (0.58) | AKT1THRBTGM2NSD2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254078-B1 | PYRAN DERIVATIVES | BASF Aktiengesellschaft (DE) | 1991-02-06 | — | — | EP | claimed |
| EP-0254078-B1 | PYRAN DERIVATIVES | BASF Aktiengesellschaft (DE) | 1991-02-06 | — | — | EP | disclosed |