Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | DUT | P33316 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | PREP | P48147 | 3/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7291568 | 0.82 | MEN1 (0.53) | MEN1NPC1RAB9AKMT2APREP | |
| SCHEMBL9875166 | 0.81 | PREP (0.60) | KMT2ADUTCYP1A2CYP2D6TSHR | |
| SCHEMBL10557781 | 0.81 | PREP (0.60) | KMT2ADUTCYP1A2CYP2D6TSHR | |
| SCHEMBL7283530 | 0.80 | MEN1 (0.51) | MEN1NPC1RAB9AKMT2AEPHX2 | |
| SCHEMBL7281110 | 0.80 | NPC1 (0.51) | MEN1NPC1RAB9AKMT2ADUT | |
| SCHEMBL3540440 | 0.79 | DPP4 (0.46) | NPC1RAB9ADUTKDM4ECYP1A2 | |
| SCHEMBL5177302 | 0.79 | DPP4 (0.46) | NPC1RAB9ADUTKDM4ECYP1A2 | |
| SCHEMBL23052796 | 0.78 | DUT (0.55) | MEN1NPC1RAB9AKMT2ADUT | |
| SCHEMBL7330019 | 0.78 | MEN1 (0.63) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL5741647 | 0.78 | MEN1 (0.63) | MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051444-A | Pyrrolidine derivatives as anti-amnesia agents | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-09-24 | — | — | US | disclosed |