Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 4/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | RXRB | P28702 | 2/20 | 0.35 |
| ▸ | RXRG | P48443 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25774449 | 0.95 | HMGCR (0.49) | HMGCRGABRA1GABRB2TP53TSHR | |
| SCHEMBL25522844 | 0.92 | HMGCR (0.47) | HMGCRGABRA1GABRB2TP53TSHR | |
| SCHEMBL16954528 | 0.86 | HMGCR (0.42) | HMGCRGABRA1GABRB2TP53TSHR | |
| SCHEMBL12786373 | 0.86 | HMGCR (0.42) | HMGCRGABRA1GABRB2TP53TSHR | |
| SCHEMBL5167911 | 0.86 | GABRA1 (0.56) | HMGCRGABRA1GABRB2TP53TSHR | |
| SCHEMBL25468603 | 0.86 | HMGCR (0.42) | HMGCRGABRA1GABRB2TP53TSHR | |
| SCHEMBL22861011 | 0.86 | HMGCR (0.42) | HMGCRGABRA1GABRB2TP53TSHR | |
| Phenol SCHEMBL28108806 | 0.84 | GABRA1 (0.44) | HMGCRGABRA1GABRB2TSHRRXRA | |
| SCHEMBL25468628 | 0.82 | HMGCR (0.44) | HMGCRATM | |
| SCHEMBL16960544 | 0.82 | HMGCR (0.41) | HMGCRGABRA1GABRB2TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3135929-A | — | — | None | — | — | JP | disclosed |
| US-20170101369-A1 | SULFONAMIDE COMPOUNDS AND THEIR USE AS STAT5 INHIBITORS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2017-04-13 | — | — | US | disclosed |
| JP-H03135929-A | SIMULTANEOUS PRODUCTION OF 2,5-DICHLOROTOLUENE AND 2,6-DICHLOROTOLUENE | KUREHA CHEM IND CO LTD | 1991-06-10 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170101369-A1 | SULFONAMIDE COMPOUNDS AND THEIR USE AS STAT5 INHIBITORS | STAT5A, STAT5B, JAK2 | HMGCR 4715/4885GABRA1 1956/4885GABRB2 1799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.