Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL355657 | 0.84 | — | — | |
| SCHEMBL13706022 | 0.81 | CNR1 (0.47) | SMN1; SMN2CNR1CNR2CHRM3ESR1 | |
| SCHEMBL94414 | 0.81 | SMN1; SMN2 (0.41) | SMN1; SMN2CNR1CNR2CHRM3ESR1 | |
| SCHEMBL73299 | 0.81 | — | — | |
| SCHEMBL9442535 | 0.80 | — | — | |
| SCHEMBL23573882 | 0.79 | SMN1; SMN2 (0.40) | SMN1; SMN2CNR1CNR2CHRM3ESR1 | |
| SCHEMBL28937212 | 0.79 | SMN1; SMN2 (0.40) | SMN1; SMN2CNR1CNR2CHRM3ESR1 | |
| SCHEMBL1363215 | 0.79 | SMN1; SMN2 (0.40) | SMN1; SMN2CNR1CNR2CHRM3ESR1 | |
| Ammonia Solution, Strong SCHEMBL4425485 | 0.79 | SMN1; SMN2 (0.40) | SMN1; SMN2CNR1CNR2CHRM3ESR1 | |
| SCHEMBL28239645 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274324-B1 | PROCESS FOR THE PREPARATION OF THIENYLETHYL AMINES, AND DITHIENYLETHYL AMINES SO OBTAINED | SANOFI (FR) | 1991-02-06 | — | — | EP | disclosed |
| EP-0274324-A1 | Process for the preparation of thienylethyl amines, and dithienylethyl amines so obtained | SANOFI (FR) | 1988-07-13 | — | — | EP | disclosed |