SCHEMBL9880232

SCHEMBL9880232

C=C(C)C(=O)OCCOC(=O)CCC(=O)N1CCN(c2ccc(C3(c4ccccc4)C=Cc4c5c(c6cc(N7CCC8CCCCC8C7)c(OC)cc6c4O3)-c3ccc(C(C)(C)C)cc3C5(C)C)cc2)CC1C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12202754 0.96
SCHEMBL15038069 0.89
SCHEMBL19901118 0.88
SCHEMBL9880231 0.86
SCHEMBL12285096 0.86
SCHEMBL9880233 0.86 L3MBTL1 (0.31)
SCHEMBL9880238 0.86
SCHEMBL9880234 0.86
SCHEMBL19901615 0.85
SCHEMBL17089918 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11789291-B2 Pupil-only photochromic contact lenses displaying desirable optics and comfort JOHNSON & JOHNSON VISION CARE, INC. (US) 2023-10-17 US disclosed
US-11789291-B2 Pupil-only photochromic contact lenses displaying desirable optics and comfort JOHNSON & JOHNSON VISION CARE, INC. (US) 2023-10-17 US disclosed
US-11724472-B2 Process for manufacture of a thermochromic contact lens material JOHNSON & JOHNSON VISION CARE, INC. (US) 2023-08-15 US disclosed
US-11724472-B2 Process for manufacture of a thermochromic contact lens material JOHNSON & JOHNSON VISION CARE, INC. (US) 2023-08-15 US disclosed
US-20210208424-A1 CONTACT LENSES DISPLAYING REDUCED INDOOR GLARE JOHNSON & JOHNSON VISION CARE (US) 2021-07-08 US disclosed
US-20210101352-A1 PROCESS FOR MANUFACTURE OF A THERMOCHROMIC CONTACT LENS MATERIAL JOHNSON & JOHNSON VISION CARE (US) 2021-04-08 US disclosed
US-20210018765-A1 PUPIL-ONLY PHOTOCHROMIC CONTACT LENSES DISPLAYING DESIRABLE OPTICS AND COMFORT JOHNSON & JOHNSON VISION CARE (US) 2021-01-21 US disclosed
US-10894374-B2 Process for manufacture of a thermochromic contact lens material JOHNSON & JOHNSON VISION CARE, INC. (US) 2021-01-19 US disclosed
US-10816822-B2 Pupil-only photochromic contact lenses displaying desirable optics and comfort JOHNSON & JOHNSON VISION CARE, INC. (US) 2020-10-27 US disclosed
US-20190250428-A1 PUPIL-ONLY PHOTOCHROMIC CONTACT LENSES DISPLAYING DESIRABLE OPTICS AND COMFORT JOHNSON & JOHNSON VISION CARE (US) 2019-08-15 US disclosed
US-8877103-B2 Process for manufacture of a thermochromic contact lens material JOHNSON & JOHNSON VISION CARE, INC. (US) 2014-11-04 US disclosed
WO-2013090220-A1 INDENO-FUSED NAPHTHOPYRANS HAVING ETHYLENICALLY UNSATURATED GROUPS PPG INDUSTRIES, INC. (US) 2013-06-20 WO disclosed
US-20120132870-A1 Indeno-Fused Naphthopyrans Having Ethylenically Unsaturated Groups TRANSITIONS OPTICAL INC. (US) 2012-05-31 US disclosed
US-20120132870-A1 Indeno-Fused Naphthopyrans Having Ethylenically Unsaturated Groups TRANSITIONS OPTICAL INC. (US) 2012-05-31 US disclosed
US-20110249234-A1 CONTACT LENSES DISPLAYING REDUCED INDOOR GLARE JOHNSON & JOHNSON VISION CARE, INC. 2011-10-13 US disclosed
US-20110249235-A1 PUPIL-ONLY PHOTOCHROMIC CONTACT LENSES DISPLAYING DESIRABLE OPTICS AND COMFORT JOHNSON & JOHNSON VISION CARE, INC. 2011-10-13 US disclosed
US-20110249235-A1 PUPIL-ONLY PHOTOCHROMIC CONTACT LENSES DISPLAYING DESIRABLE OPTICS AND COMFORT JOHNSON & JOHNSON VISION CARE, INC. 2011-10-13 US disclosed
US-20110249234-A1 CONTACT LENSES DISPLAYING REDUCED INDOOR GLARE JOHNSON & JOHNSON VISION CARE, INC. 2011-10-13 US disclosed
US-20110248415-A1 PROCESS FOR MANUFACTURE OF A THERMOCHROMIC CONTACT LENS MATERIAL JOHNSON & JOHNSON VISION CARE, INC. 2011-10-13 US disclosed
US-20110248415-A1 PROCESS FOR MANUFACTURE OF A THERMOCHROMIC CONTACT LENS MATERIAL JOHNSON & JOHNSON VISION CARE, INC. 2011-10-13 US disclosed