⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3258913 | 0.93 | — | — | |
| SCHEMBL9683531 | 0.84 | — | — | |
| Formaldehyde SCHEMBL28242913 | 0.76 | ADH1B (0.44) | — | |
| SCHEMBL6567934 | 0.75 | — | — | |
| SCHEMBL28250679 | 0.73 | — | — | |
| SCHEMBL28325031 | 0.73 | — | — | |
| SCHEMBL11114293 | 0.71 | — | — | |
| SCHEMBL13659141 | 0.71 | — | — | |
| SCHEMBL29090592 | 0.70 | — | — | |
| SCHEMBL912854 | 0.69 | TSHR (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116440900-A | Ternary catalyst, preparation method and application | 东风汽车集团股份有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-102516094-A | Production method of butyl amide ethenol | NINGXIA DONGKE PETRIFACTION CO LTD | 2012-06-27 | — | — | CN | claimed |
| US-12163124-B2 | Method for gene editing | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-12-10 | — | — | US | disclosed |
| CN-116440900-A | Ternary catalyst, preparation method and application | 东风汽车集团股份有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-111228509-A | Bispecific anti-hapten/anti-blood brain barrier receptor antibodies, complexes thereof and their use as blood brain barrier shuttles | 豪夫迈·罗氏有限公司 | 2020-06-05 | — | — | CN | disclosed |
| CN-105899540-B | Bispecific anti-hapten/anti-blood-brain barrier receptor antibodies, complexes thereof and their use as blood-brain barrier shuttles | 豪夫迈·罗氏有限公司 | 2020-02-07 | — | — | CN | disclosed |
| EP-2823821-B1 | ANTIBODY SPECIFICALLY BINDING TO DIGOXIGENIN | HOFFMANN LA ROCHE (CH) | 2017-02-22 | — | — | EP | disclosed |
| US-9574016-B2 | Complex of bi-specific antibody and digoxigenin conjugated to a therapeutic or diagnostic agent | HOFFMANN-LA ROCHE INC. (US) | 2017-02-21 | — | — | US | disclosed |
| CN-105899540-A | Bispecific anti-hapten/anti-blood-brain barrier receptor antibodies, complexes thereof and their use as blood-brain barrier shuttles | 豪夫迈·罗氏有限公司 | 2016-08-24 | — | — | CN | disclosed |
| US-20160009823-A1 | COMPLEX OF BI-SPECIFIC ANTIBODY AND DIGOXIGENIN CONJUGATED TO A THERAPEUTIC OR DIAGNOSTIC AGENT | HOFFMANN-LA ROCHE INC. (US) | 2016-01-14 | — | — | US | disclosed |
| EP-2451480-B1 | A COMPLEX OF BI-SPECIFIC ANTIBODY AND DIGOXIGENIN CONJUGATED TO A THERAPEUTIC OR DIAGNOSTIC AGENT | HOFFMANN LA ROCHE (CH) | 2015-08-19 | — | — | EP | disclosed |
| US-20120282280-A1 | BI-SPECIFIC DIGOXIGENIN BINDING ANTIBODIES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-11-08 | — | — | US | disclosed |
| US-20120269723-A1 | COMPLEX OF BI-SPECIFIC ANTIBODY AND DIGOXIGENIN CONJUGATED TO A THERAPEUTIC OR DIAGNOSTIC AGENT | F. HOFFMANN-LA ROCHE AG (CH) | 2012-10-25 | — | — | US | disclosed |
| CN-102614528-A | Polyconjugates for in vivo delivery of polynucleotides | ARROWHEAD MADISON INC | 2012-08-01 | — | — | CN | disclosed |
| CN-102516094-A | Production method of butyl amide ethenol | NINGXIA DONGKE PETRIFACTION CO LTD | 2012-06-27 | — | — | CN | disclosed |
| EP-2451480-A1 | A COMPLEX OF BI-SPECIFIC ANTIBODY AND DIGOXIGENIN CONJUGATED TO A THERAPEUTIC OR DIAGNOSTIC AGENT | F. Hoffmann-La Roche AG (CH) | 2012-05-16 | — | — | EP | disclosed |
| EP-2451479-A1 | BI-SPECIFIC DIGOXIGENIN BINDING ANTIBODIES | F. Hoffmann-La Roche AG (CH) | 2012-05-16 | — | — | EP | disclosed |
| WO-2011003557-A1 | A COMPLEX OF BI-SPECIFIC ANTIBODY AND DIGOXIGENIN CONJUGATED TO A THERAPEUTIC OR DIAGNOSTIC AGENT | F. HOFFMANN-LA ROCHE AG (CH) | 2011-01-13 | — | — | WO | disclosed |
| WO-2011003780-A1 | BI-SPECIFIC DIGOXIGENIN BINDING ANTIBODIES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-01-13 | — | — | WO | disclosed |
| CN-101500548-A | Polyconjugates for in vivo delivery of polynucleotides | HOFFMANN LA ROCHE (CH) | 2009-08-05 | — | — | CN | disclosed |