SCHEMBL988583

SCHEMBL988583

CCCC[Sn](Br)(CCCC)O[Sn](Br)(CCCC)CCCC

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
LMNA P02545 1/20 0.33
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1042268 0.89 TSHR (0.42) TSHRLMNATHRB
SCHEMBL8618779 0.83
SCHEMBL5897382 0.71
SCHEMBL2346 0.71 TSHR (0.40) TSHRLMNATHRB
SCHEMBL154034 0.71 TSHR (0.40) TSHRLMNATHRB
Water SCHEMBL5897582 0.69 TSHR (0.38) TSHRLMNATHRB
SCHEMBL11798452 0.69
SCHEMBL19183 0.69 TSHR (0.38) TSHRLMNATHRB
SCHEMBL11435810 0.67 TSHR (0.35) TSHRLMNATHRB
SCHEMBL11295913 0.67 TSHR (0.35) TSHRLMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1740636-A1 CATALYSTS AND METHODS FOR POLYMERIZING MACROCYCLIC OLIGOMERS Dow Gloval Technologies Inc. (US) 2007-01-10 EP claimed
US-20060025562-A1 Catalysts and methods for polymerizing macrocyclic oligomers DOW CHEMICAL COMPANY, THE 2006-02-02 US claimed
WO-2005105889-A1 CATALYSTS AND METHODS FOR POLYMERIZING MACROCYCLIC OLIGOMERS DOW GLOBAL TECHNOLOGIES, INC. (US) 2005-11-10 WO claimed
US-5461139-A Ring-opening polymerization of of beta-butyrolactone and cyclic carbonate using distannoxane catalyst TAKASAGO INTERNATIONAL CORPORATION (JP) 1995-10-24 US claimed
EP-2275405-B1 PROCESS FOR PRODUCING ISOCYANATE USING DIARYL CARBONATE ASAHI CHEMICAL IND (JP) 2019-04-24 EP disclosed
US-8895774-B2 Process for producing isocyanates using diaryl carbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2014-11-25 US disclosed
US-20110054211-A1 PROCESS FOR PRODUCING ISOCYANATES USING DIARYL CARBONATE ASAHI KASEI CHEMICALS CORPORATION (JP) 2011-03-03 US disclosed
EP-2275405-A1 PROCESS FOR PRODUCING ISOCYANATE USING DIARYL CARBONATE Asahi Kasei Chemicals Corporation (JP) 2011-01-19 EP disclosed
WO-2008021035-A9 POLYMERS OF MACROCYCLIC OLIGOMERS CONTAINING HIGHLY EXPANDED GRAPHITE DOW GLOBAL TECHNOLOGIES INC (US) 2008-04-10 WO disclosed
WO-2008021035-A1 POLYMERS OF MACROCYCLIC OLIGOMERS CONTAINING HIGHLY EXPANDED GRAPHITE DOW GLOBAL TECHNOLOGIES, INC. (US) 2008-02-21 WO disclosed
US-20080039573-A1 Polymers of macrocyclic oligomers containing highly expanded graphite DOW GLOBAL TECHNOLOGIES, INC. 2008-02-14 US disclosed
EP-1773927-A1 POLYMERIZABLE MACROCYCLIC OLIGOMER MASTERBATCHES CONTAINING DISPERSED FILLERS Dow Gloval Technologies Inc. (US) 2007-04-18 EP disclosed
CN-1469777-A Use of tin derivatives as catalysts for transforming carbamates, carbamate compositions comprising said catalyst and method for transforming carbamates �Ϻ���ͨ��ѧ 2004-01-21 CN disclosed
EP-0601885-B1 Biodegradable optically active polymer of lactones and process for production thereof TAKASAGO PERFUMERY CO LTD (JP) 1998-06-03 EP disclosed
EP-0612780-B1 Process for producing poly(3-hydroxybutyric acid) TAKASAGO PERFUMERY CO LTD (JP) 1998-05-20 EP disclosed
US-5516883-A POLYLACTONES TAKASAGO INTERNATIONAL CORPORATION (JP) 1996-05-14 US disclosed
US-5461139-A Ring-opening polymerization of of beta-butyrolactone and cyclic carbonate using distannoxane catalyst TAKASAGO INTERNATIONAL CORPORATION (JP) 1995-10-24 US disclosed
US-5430125-A Ring opening polymerization of beta butyrolalactone in the presence of a distannoxane derivative, a tin carboxylate and a di-lower alkyltin oxide TAKASAGO INTERNATIONAL CORPORATION (JP) 1995-07-04 US disclosed
EP-0640637-A1 Biodegradable optically-active polyester carbonates Takasago International Corporation (JP) 1995-03-01 EP disclosed
EP-0612780-A2 Process for producing poly(3-hydroxybutyric acid) Takasago International Corporation (JP) 1994-08-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110054211-A1 PROCESS FOR PRODUCING ISOCYANATES USING DIARYL CARBONATE PAH, AADAC, PHGDH TSHR 4813/4885LMNA 3368/4885THRB 4818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.