⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL988583 | 0.83 | TSHR (0.33) | — | |
| SCHEMBL1042268 | 0.73 | TSHR (0.42) | — | |
| SCHEMBL6271386 | 0.73 | — | — | |
| SCHEMBL5897575 | 0.69 | — | — | |
| SCHEMBL7891631 | 0.68 | — | — | |
| SCHEMBL1554708 | 0.66 | ALDH1A1 (0.36) | — | |
| SCHEMBL6924350 | 0.65 | TSHR (0.33) | — | |
| SCHEMBL5897382 | 0.63 | — | — | |
| SCHEMBL154034 | 0.63 | TSHR (0.40) | — | |
| SCHEMBL2346 | 0.63 | TSHR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5461139-A | Ring-opening polymerization of of beta-butyrolactone and cyclic carbonate using distannoxane catalyst | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1995-10-24 | — | — | US | claimed |
| EP-0601885-B1 | Biodegradable optically active polymer of lactones and process for production thereof | TAKASAGO PERFUMERY CO LTD (JP) | 1998-06-03 | — | — | EP | disclosed |
| EP-0612780-B1 | Process for producing poly(3-hydroxybutyric acid) | TAKASAGO PERFUMERY CO LTD (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5516883-A | POLYLACTONES | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5461139-A | Ring-opening polymerization of of beta-butyrolactone and cyclic carbonate using distannoxane catalyst | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1995-10-24 | — | — | US | disclosed |
| US-5430125-A | Ring opening polymerization of beta butyrolalactone in the presence of a distannoxane derivative, a tin carboxylate and a di-lower alkyltin oxide | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1995-07-04 | — | — | US | disclosed |
| EP-0640637-A1 | Biodegradable optically-active polyester carbonates | Takasago International Corporation (JP) | 1995-03-01 | — | — | EP | disclosed |
| EP-0612780-A2 | Process for producing poly(3-hydroxybutyric acid) | Takasago International Corporation (JP) | 1994-08-31 | — | — | EP | disclosed |
| US-4035403-A | BACTERICIDES | CINCINNATI MILACRON, INC. (US) | 1977-07-12 | — | — | US | disclosed |
| US-4021407-A | DISCOLORATION INHIBITION | CINCINNATI MILACRON, INC. (US) | 1977-05-03 | — | — | US | disclosed |