SCHEMBL9890067

SCHEMBL9890067

c1ccc(-c2ccc3c(c2)c2cc(-c4ccc5oc6cc7c(cc6c5c4)oc4ccc(-c5nc(-c6ccccc6)cc(-c6ccccc6)n5)cc47)ccc2n3-c2ccccc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.38
KMT2A Q03164 5/20 0.38
ALDH1A1 P00352 4/20 0.38
MAPT P10636 4/20 0.38
HPGD P15428 3/20 0.38
NTSR1 P30989 1/20 0.38
KDM4E B2RXH2 3/20 0.37
LMNA P02545 3/20 0.37
PGR P06401 1/20 0.36
PLA2G2A P14555 2/20 0.35
PLA2G4A P47712 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
GAA P10253 2/20 0.35
SIRT2 Q8IXJ6 1/20 0.35
SIRT1 Q96EB6 1/20 0.35
GLA P06280 1/20 0.35
ATM Q13315 1/20 0.34
PRKDC P78527 3/20 0.34
NPC1 O15118 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9890064 0.98 MEN1 (0.40) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL9890069 0.94 MEN1 (0.38) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL26356039 0.93 KDM4E (0.44) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL20248611 0.93 KDM4E (0.44) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL9890073 0.92 MEN1 (0.39) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL9889999 0.92 KDM4E (0.41) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL26356088 0.91 KDM4E (0.40) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL16185476 0.91 MAPT (0.40) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL26356035 0.91 KDM4E (0.42) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL19933673 0.91 KDM4E (0.42) MEN1KMT2AALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120138915-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed
US-20120138915-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed