SCHEMBL19933673

SCHEMBL19933673

c1ccc(-c2cc(-c3ccccc3)nc(-c3cccc(-c4ccc5oc6ccc(-c7ccc8c(c7)c7ccccc7n8-c7ccccc7)cc6c5c4)c3)n2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
ATM Q13315 1/20 0.42
KMT2A Q03164 5/20 0.38
MEN1 O00255 4/20 0.38
ALDH1A1 P00352 4/20 0.38
MAPT P10636 4/20 0.38
HPGD P15428 4/20 0.38
LMNA P02545 2/20 0.38
PLA2G2A P14555 3/20 0.38
PLA2G4A P47712 3/20 0.38
PLA2G10 O15496 1/20 0.38
PTGER4 P35408 1/20 0.37
NTSR1 P30989 1/20 0.37
SIRT2 Q8IXJ6 1/20 0.36
SIRT1 Q96EB6 1/20 0.36
GLA P06280 1/20 0.36
PRKDC P78527 1/20 0.34
MAPK1 P28482 2/20 0.33
CHEK2 O96017 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20248611 0.98 KDM4E (0.44) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL26356039 0.98 KDM4E (0.44) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL26356035 0.95 KDM4E (0.42) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL15294141 0.94 PLA2G2A (0.38) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL16805646 0.94 PLA2G2A (0.38) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL16805650 0.94 PLA2G2A (0.38) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL9889999 0.94 KDM4E (0.41) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL15294134 0.93 PLA2G2A (0.37) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL26356088 0.93 KDM4E (0.40) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL16185691 0.93 PLA2G2A (0.40) KDM4EL3MBTL1ATMKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917903-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 US disclosed
US-11917903-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 US disclosed
US-20230320191-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-10-05 US disclosed
US-20230320191-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-10-05 US disclosed
US-11659763-B2 Metal complexes MERCK PATENT GMBH 2023-05-23 US disclosed
US-11659763-B2 Metal complexes MERCK PATENT GMBH 2023-05-23 US disclosed
US-11569458-B2 Metal complexes MERCK PATENT GMBH (DE) 2023-01-31 US disclosed
US-11535640-B2 Metal complexes MERCK PATENT GMBH (DE) 2022-12-27 US disclosed
US-11322696-B2 Metal complexes MERCK PATENT GMBH (DE) 2022-05-03 US disclosed
EP-3601304-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2021-10-27 EP disclosed
EP-3515925-B1 BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-10-21 EP disclosed
US-20200207794-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2020-07-02 US disclosed
US-20200052213-A1 BINUCLEAR METAL COMPLEXES AND ELECTRONIC DEVICES, IN PARTICULAR ORGANIC ELECTROLUMINESCENT DEVICES CONTAINING SAID METAL COMPLEXES MERCK PATENT GMBH (DE) 2020-02-13 US disclosed
US-20190292210-A1 BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-09-26 US disclosed
US-20190252628-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-08-15 US disclosed
US-20190202851-A1 BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-07-04 US disclosed
WO-2019020538-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-01-31 WO disclosed
WO-2018069197-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2018-04-19 WO disclosed
WO-2018054798-A1 BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2018-03-29 WO disclosed
WO-2018041769-A1 BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2018-03-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190202851-A1 BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES PARN, PUF60, PARG KDM4E 4048/4885L3MBTL1 1520/4885ATM 3697/4885
US-20190252628-A1 METAL COMPLEXES AP1M1, AP2M1, AP3M1 KDM4E 3877/4885L3MBTL1 3031/4885ATM 4131/4885
US-20190292210-A1 BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES AP2M1, MCU, AP3M1 KDM4E 4613/4885L3MBTL1 2504/4885ATM 4246/4885
US-20230320191-A1 METAL COMPLEXES IMMT, MCU, SOD1 KDM4E 4470/4885L3MBTL1 3259/4885ATM 4048/4885
US-20200207794-A1 METAL COMPLEXES IMMT, MCU, SOD1 KDM4E 4470/4885L3MBTL1 3259/4885ATM 4048/4885
US-11322696-B2 Metal complexes AP1M1, AP3M1, AP2M1 KDM4E 4376/4885L3MBTL1 3543/4885ATM 4372/4885
US-11535640-B2 Metal complexes IMMT, MCU, SOD1 KDM4E 4470/4885L3MBTL1 3259/4885ATM 4048/4885
US-11659763-B2 Metal complexes IMMT, MCU, SOD1 KDM4E 4470/4885L3MBTL1 3259/4885ATM 4048/4885
US-11569458-B2 Metal complexes IMMT, MCU, SOD1 KDM4E 4470/4885L3MBTL1 3259/4885ATM 4048/4885
US-20200052213-A1 BINUCLEAR METAL COMPLEXES AND ELECTRONIC DEVICES, IN PARTICULAR ORGANIC ELECTROLUMINESCENT DEVICES CONTAINING SAID METAL COMPLEXES BICRA, NCLN, IMMT KDM4E 3160/4885L3MBTL1 3344/4885ATM 4082/4885
US-11917903-B2 Metal complexes NCLN, BICRA, AP3M1 KDM4E 3870/4885L3MBTL1 2532/4885ATM 3416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.