SCHEMBL9890209

SCHEMBL9890209

c1ccc(-n2c3ccc(-n4c5ccccc5c5ccccc54)cc3c3cc4oc5ccc(-n6c7ccccc7c7ccccc76)cc5c4cc32)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
ATM Q13315 1/20 0.51
SIRT2 Q8IXJ6 1/20 0.36
SIRT1 Q96EB6 1/20 0.36
ALDH1A1 P00352 4/20 0.36
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
TSHR P16473 2/20 0.36
HSD17B10 Q99714 2/20 0.36
POLB P06746 1/20 0.36
BRCA1 P38398 1/20 0.36
PTPN1 P18031 2/20 0.35
HPGD P15428 2/20 0.35
AHR P35869 2/20 0.35
NPC1 O15118 1/20 0.35
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
EDNRB P24530 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17245948 0.96 KDM4E (0.50) KDM4EL3MBTL1ATMSIRT2SIRT1
SCHEMBL16171188 0.96 KDM4E (0.50) KDM4EL3MBTL1ATMSIRT2SIRT1
SCHEMBL12175621 0.96 KDM4E (0.56) KDM4EL3MBTL1ATMSIRT2SIRT1
SCHEMBL9890220 0.94 KDM4E (0.51) KDM4EL3MBTL1ATMSIRT2SIRT1
SCHEMBL27428318 0.94 KDM4E (0.51) KDM4EL3MBTL1ATMSIRT2SIRT1
SCHEMBL12811614 0.94 KDM4E (0.51) KDM4EL3MBTL1ATMSIRT2SIRT1
SCHEMBL16171208 0.93 KDM4E (0.47) KDM4EL3MBTL1ATMSIRT2SIRT1
SCHEMBL1637164 0.93 KDM4E (0.53) KDM4EL3MBTL1ATMSIRT2SIRT1
SCHEMBL9890071 0.92 KDM4E (0.49) KDM4EL3MBTL1ATMSIRT2SIRT1
SCHEMBL17245935 0.91 MAPT (0.44) KDM4EL3MBTL1ATMALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9647220-B2 Organic multicolor light-emitting apparatus SONY CORPORATION (JP) 2017-05-09 US disclosed
US-9647220-B2 Organic multicolor light-emitting apparatus SONY CORPORATION (JP) 2017-05-09 US disclosed
US-20160276602-A1 ORGANIC MULTICOLOR LIGHT-EMITTING APPARATUS SONY CORPORATION (JP) 2016-09-22 US disclosed
US-20160276602-A1 ORGANIC MULTICOLOR LIGHT-EMITTING APPARATUS SONY CORPORATION (JP) 2016-09-22 US disclosed
US-20130020563-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-01-24 US disclosed
US-20130020563-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-01-24 US disclosed
US-8318323-B2 Polycyclic compounds and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2012-11-27 US disclosed
US-8318323-B2 Polycyclic compounds and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2012-11-27 US disclosed
US-20120138915-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed
US-20120138915-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed
EP-2301921-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2011-03-30 EP disclosed
US-20100012931-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130020563-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME KCNC1, EED, BMI1 KDM4E 990/4885L3MBTL1 709/4885ATM 3103/4885
US-20100012931-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME KCNC1, EED, BMI1 KDM4E 990/4885L3MBTL1 709/4885ATM 3103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.