SCHEMBL9890221

SCHEMBL9890221

c1ccc2c(c1)oc1ccc(-n3c4ccccc4c4cc5c(cc43)c3cc(-n4c6ccccc6c6ccccc64)ccc3n5-c3ccc4oc5ccccc5c4c3)cc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.45
KDM4E B2RXH2 4/20 0.45
ALDH1A1 P00352 4/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
HPGD P15428 3/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 1/20 0.45
ATM Q13315 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
AHR P35869 2/20 0.41
CYP1A2 P05177 2/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
CHRNA7 P36544 1/20 0.36
KCNH2 Q12809 1/20 0.36
LMNA P02545 1/20 0.35
MAOA P21397 3/20 0.35
GLA P06280 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1636722 0.98 MAPT (0.46) MAPTKDM4EALDH1A1SMN1; SMN2HPGD
SCHEMBL1635406 0.97 KDM4E (0.47) MAPTKDM4EALDH1A1SMN1; SMN2HPGD
SCHEMBL21671308 0.97 MAPT (0.47) MAPTKDM4EALDH1A1SMN1; SMN2HPGD
SCHEMBL10449855 0.97 MAPT (0.47) MAPTKDM4EALDH1A1SMN1; SMN2HPGD
SCHEMBL14679589 0.97 MAPT (0.47) MAPTKDM4EALDH1A1SMN1; SMN2HPGD
SCHEMBL3664059 0.97 MAPT (0.47) MAPTKDM4EALDH1A1SMN1; SMN2HPGD
SCHEMBL27428318 0.96 KDM4E (0.51) MAPTKDM4EALDH1A1SMN1; SMN2HPGD
SCHEMBL9890220 0.96 KDM4E (0.51) MAPTKDM4EALDH1A1SMN1; SMN2HPGD
SCHEMBL17245935 0.95 MAPT (0.44) MAPTKDM4EALDH1A1SMN1; SMN2HPGD
SCHEMBL9890470 0.95 MAPT (0.44) MAPTKDM4EALDH1A1SMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9647220-B2 Organic multicolor light-emitting apparatus SONY CORPORATION (JP) 2017-05-09 US disclosed
US-9647220-B2 Organic multicolor light-emitting apparatus SONY CORPORATION (JP) 2017-05-09 US disclosed
US-20160276602-A1 ORGANIC MULTICOLOR LIGHT-EMITTING APPARATUS SONY CORPORATION (JP) 2016-09-22 US disclosed
US-20160276602-A1 ORGANIC MULTICOLOR LIGHT-EMITTING APPARATUS SONY CORPORATION (JP) 2016-09-22 US disclosed
US-20130020563-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-01-24 US disclosed
US-20130020563-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-01-24 US disclosed
US-8318323-B2 Polycyclic compounds and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2012-11-27 US disclosed
US-8318323-B2 Polycyclic compounds and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2012-11-27 US disclosed
US-20120138915-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed
US-20120138915-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed
EP-2301921-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2011-03-30 EP disclosed
US-20100012931-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130020563-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME KCNC1, EED, BMI1 MAPT 1303/4885KDM4E 990/4885ALDH1A1 1594/4885
US-20100012931-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME KCNC1, EED, BMI1 MAPT 1303/4885KDM4E 990/4885ALDH1A1 1594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.