Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA4 | P22748 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12948845 | 0.89 | PTPN1 (0.45) | PTPN1PTGDR2CA12CA1CA2 | |
| SCHEMBL990116 | 0.87 | PTPN1 (0.43) | PTPN1PTGDR2CA12CA1CA2 | |
| SCHEMBL2770497 | 0.84 | PTGDR2 (0.44) | PTPN1PTGDR2 | |
| SCHEMBL2772335 | 0.83 | PTGDR2 (0.47) | PTPN1PTGDR2 | |
| SCHEMBL2773052 | 0.80 | PTGDR2 (0.47) | PTPN1PTGDR2TAS2R14KEAP1NFE2L2 | |
| SCHEMBL13160853 | 0.80 | PTGDR2 (0.43) | PTPN1PTGDR2CA12CA1CA2 | |
| SCHEMBL12948844 | 0.80 | PTGDR2 (0.47) | PTPN1PTGDR2CA12CA1CA2 | |
| SCHEMBL2770744 | 0.80 | PTGDR2 (0.45) | PTPN1PTGDR2TAS2R14KEAP1NFE2L2 | |
| SCHEMBL2771457 | 0.80 | TAS2R14 (0.47) | PTPN1PTGDR2TAS2R14KEAP1NFE2L2 | |
| SCHEMBL2769543 | 0.78 | PTGDR2 (0.43) | PTPN1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011002814-A2 | BIARYL OXYACETIC ACID COMPOUNDS | LIGAND PHARMACEUTICALS INC. (US) | 2011-01-06 | — | — | WO | claimed |
| WO-2011002814-A2 | BIARYL OXYACETIC ACID COMPOUNDS | LIGAND PHARMACEUTICALS INC. (US) | 2011-01-06 | — | — | WO | disclosed |