Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | LPL | P06858 | 1/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18856963 | 0.87 | TAAR1 (0.52) | TAAR1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL6546733 | 0.84 | TAAR1 (0.68) | TAAR1ALDH1A1TP53CYP2A6LPL | |
| SCHEMBL10685072 | 0.84 | ALDH1A1 (0.69) | TAAR1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL17148393 | 0.83 | TAAR1 (0.54) | TAAR1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL20415542 | 0.83 | TAAR1 (0.48) | TAAR1ALDH1A1HSD17B10TP53LPL | |
| SCHEMBL9486125 | 0.82 | ALDH1A1 (0.52) | TAAR1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL36295 | 0.80 | TP53 (0.67) | TAAR1ALDH1A1TP53CYP2A6LPL | |
| SCHEMBL6271714 | 0.80 | TAAR1 (0.56) | TAAR1ALDH1A1TP53CYP2A6LPL | |
| SCHEMBL10575050 | 0.79 | TAAR1 (0.62) | TAAR1ALDH1A1HSD17B10TP53CYP2A6 | |
| SCHEMBL11154258 | 0.79 | TAAR1 (0.62) | TAAR1ALDH1A1TP53CYP2A6LPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024050742-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING KRAS G12D VIA UBIQUITIN PROTEASOME PATHWAY | NIKANG THERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |
| WO-2017082924-A1 | PEPTIDE AND PEPTIDE MIMETIC BINDING ANTAGONISTS OF POLO-LIKE KINASE 1 POLO BOX DOMAIN AND METHODS OF USE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 2017-05-18 | — | — | WO | disclosed |
| WO-2014111949-A1 | INTERMEDIATES AND PROCESS FOR THE PREPARATION OF HIGH PURITY FINGOLIMOD HYDROCHLORIDE | NATCO PHARMA LIMITED (IN) | 2014-07-24 | — | — | WO | disclosed |
| US-20120141513-A1 | DEUTERATED FINGOLIMOD | CONCERT PHARMACEUTICALS INC. | 2012-06-07 | — | — | US | disclosed |
| WO-2011031934-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2011-03-17 | — | — | WO | disclosed |
| US-20090176744-A1 | Deuterated fingolimod | CONCERT PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120141513-A1 | DEUTERATED FINGOLIMOD | S1PR1, S1PR3, S1PR4 | TAAR1 140/4885ALDH1A1 2873/4885HPGD 1817/4885 |
| US-20090176744-A1 | Deuterated fingolimod | S1PR1, S1PR3, S1PR4 | TAAR1 140/4885ALDH1A1 2873/4885HPGD 1817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.