SCHEMBL9891699

SCHEMBL9891699

c1cc(N(c2ccc(COC3CCCCO3)cc2)c2ccc(COC3CCCCO3)cc2)ccc1CCc1ccc(N(c2ccc(COC3CCCCO3)cc2)c2ccc(COC3CCCCO3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ICAM1 P05362 1/20 0.39
SELE P16581 1/20 0.39
KDM4C Q9H3R0 1/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CREBBP Q92793 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
EP300 Q09472 1/20 0.34
MGLL Q99685 2/20 0.33
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TACR1 P25103 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14650387 0.96 ICAM1 (0.41) ICAM1SELEKDM4CMEN1KMT2A
SCHEMBL15831435 0.94 ICAM1 (0.38) ICAM1SELEKDM4CMEN1KMT2A
SCHEMBL14952712 0.94 ICAM1 (0.37) ICAM1SELEKDM4CMEN1KMT2A
SCHEMBL14650435 0.91 ICAM1 (0.39) ICAM1SELEKDM4CMEN1KMT2A
SCHEMBL14650386 0.91 ICAM1 (0.39) ICAM1SELEKDM4CMEN1KMT2A
SCHEMBL14650423 0.91 ICAM1 (0.39) ICAM1SELEKDM4CMEN1KMT2A
SCHEMBL15831437 0.91 ICAM1 (0.39) ICAM1SELEKDM4CMEN1KMT2A
SCHEMBL14650438 0.91 ICAM1 (0.39) ICAM1SELEKDM4CMEN1KMT2A
SCHEMBL9891694 0.91 ICAM1 (0.39) ICAM1SELEKDM4CMEN1KMT2A
SCHEMBL14650382 0.91 ICAM1 (0.39) ICAM1SELEKDM4CMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9201319-B2 Image bearing member, manufacturing method of the same, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2015-12-01 US disclosed
US-9201319-B2 Image bearing member, manufacturing method of the same, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2015-12-01 US disclosed
US-8912348-B2 Tetrahydropyranyl compound and method for producing the tetrahydropyranyl compound RICOH COMPANY, LTD. (JP) 2014-12-16 US disclosed
US-8912348-B2 Tetrahydropyranyl compound and method for producing the tetrahydropyranyl compound RICOH COMPANY, LTD. (JP) 2014-12-16 US disclosed
US-8771909-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2014-07-08 US disclosed
US-8771909-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2014-07-08 US disclosed
US-20140178810-A1 IMAGE BEARING MEMBER, MANUFACTURING METHOD OF THE SAME, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2014-06-26 US disclosed
US-20140178810-A1 IMAGE BEARING MEMBER, MANUFACTURING METHOD OF THE SAME, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2014-06-26 US disclosed
US-8679712-B2 Photoreceptor and image forming method, image forming apparatus, and process cartridge using the photoreceptor RICOH COMPANY, LTD. (JP) 2014-03-25 US disclosed
US-8679712-B2 Photoreceptor and image forming method, image forming apparatus, and process cartridge using the photoreceptor RICOH COMPANY, LTD. (JP) 2014-03-25 US disclosed
US-20130295497-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-11-07 US disclosed
US-20130295497-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-11-07 US disclosed
US-20130295496-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE USING THE ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR RICOH COMPANY, LTD. (JP) 2013-11-07 US disclosed
US-20130295496-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE USING THE ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR RICOH COMPANY, LTD. (JP) 2013-11-07 US disclosed
US-20130122409-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-05-16 US disclosed
US-20130122409-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-05-16 US disclosed
US-20130022903-A1 PHOTORECEPTOR AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE USING THE PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2013-01-24 US disclosed
US-20130022903-A1 PHOTORECEPTOR AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE USING THE PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2013-01-24 US disclosed
US-20120142948-A1 TETRAHYDROPYRANYL COMPOUND AND METHOD FOR PRODUCING THE TETRAHYDROPYRANYL COMPOUND RICOH COMPANY, LTD. (JP) 2012-06-07 US disclosed
US-20120142948-A1 TETRAHYDROPYRANYL COMPOUND AND METHOD FOR PRODUCING THE TETRAHYDROPYRANYL COMPOUND RICOH COMPANY, LTD. (JP) 2012-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120142948-A1 TETRAHYDROPYRANYL COMPOUND AND METHOD FOR PRODUCING THE TETRAHYDROPYRANYL COMPOUND CYP4A11, CYP11B1, CYP11B2 ICAM1 4603/4885SELE 4853/4885KDM4C 690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.