Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.44 |
| ▸ | IDH1 | O75874 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LCAT | P04180 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16480490 | 0.83 | HRH3 (0.40) | HRH3IDH1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL9891784 | 0.82 | NPC1 (0.42) | HRH3IDH1 | |
| SCHEMBL9891779 | 0.81 | HRH3 (0.42) | HRH3IDH1 | |
| SCHEMBL9891778 | 0.81 | GAA (0.42) | IDH1KDM4EALDH1A1SRD5A1MAPT | |
| SCHEMBL9891754 | 0.79 | POLB (0.50) | ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL9108258 | 0.78 | IDH1 (0.43) | HRH3IDH1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL9891783 | 0.78 | CNR1 (0.51) | HRH3IDH1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL9891781 | 0.78 | CNR1 (0.50) | IDH1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL9108249 | 0.78 | IDH1 (0.43) | HRH3IDH1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL9891782 | 0.75 | KDM4E (0.46) | HRH3IDH1KDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629157-B2 | Pyrrolidine compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-14 | — | — | US | disclosed |
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | HRH3 236/4885IDH1 4245/4885KDM4E 2527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.