Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.65 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.65 |
| ▸ | TYR | P14679 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.50 |
| ▸ | GCK | P35557 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | FPR1 | P21462 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9891912 | 0.93 | ADORA1 (0.57) | ADORA1TMIGD3TYRADORA2AGCK | |
| SCHEMBL16480470 | 0.83 | ADORA1 (0.70) | ADORA1TMIGD3TYRADORA2ALMNA | |
| SCHEMBL4969168 | 0.81 | ADORA1 (0.68) | ADORA1TMIGD3ADORA2AGCKLMNA | |
| SCHEMBL9893165 | 0.79 | ADORA1 (0.65) | ADORA1TMIGD3ADORA2AGCKLMNA | |
| SCHEMBL9892352 | 0.79 | ADORA1 (1.00) | ADORA1TMIGD3TYRADORA2AGCK | |
| SCHEMBL16373558 | 0.77 | ADORA1 (0.62) | ADORA1TMIGD3ADORA2AGCKLMNA | |
| SCHEMBL9893178 | 0.76 | TMIGD3 (0.61) | ADORA1TMIGD3ADORA2ALMNARAB9A | |
| SCHEMBL9570949 | 0.76 | MAPT (0.60) | TYRLMNARAB9ANPC1ALDH1A1 | |
| SCHEMBL17131644 | 0.76 | NPC1 (0.54) | ADORA1TMIGD3TYRADORA2AGCK | |
| SCHEMBL4304336 | 0.75 | ADORA1 (0.68) | ADORA1TMIGD3ADORA2AGCKRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629157-B2 | Pyrrolidine compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-14 | — | — | US | disclosed |
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | ADORA1 278/4885TMIGD3 1180/4885TYR 2678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.