Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.62 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.59 |
| ▸ | PRKACA | P17612 | 1/20 | 0.58 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.58 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | TNF | P01375 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20641347 | 0.83 | HTT (0.62) | HTTCYP1A2CYP2D6POLBCXCR4 | |
| SCHEMBL13127436 | 0.81 | LMNA (0.73) | HTTPRKACARPS6KB1GSK3BROCK1 | |
| SCHEMBL1992429 | 0.80 | CYP1A2 (1.00) | HTTCYP1A2CYP2D6POLBCXCR4 | |
| SCHEMBL13497731 | 0.80 | LMNA (0.54) | HTTCYP1A2CYP2D6POLBPRKACA | |
| SCHEMBL23319549 | 0.80 | HTT (0.62) | HTTCYP1A2CYP2D6POLBCXCR4 | |
| SCHEMBL6199065 | 0.80 | CXCR4 (0.85) | HTTCYP1A2CYP2D6POLBCXCR4 | |
| SCHEMBL12565557 | 0.79 | LMNA (0.56) | HTTCYP1A2CYP2D6POLBPRKACA | |
| SCHEMBL1537633 | 0.79 | LMNA (0.57) | HTTPOLBPRKACARPS6KB1GSK3B | |
| SCHEMBL18250343 | 0.79 | LMNA (0.65) | HTTPOLBPRKACARPS6KB1GSK3B | |
| SCHEMBL13071434 | 0.79 | LMNA (0.56) | HTTPOLBPRKACARPS6KB1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4221872-A1 | MEMBRANES FOR REMOVING METALLIC SPECIES FROM AMINES | Entegris, Inc. (US) | 2023-08-09 | — | — | EP | disclosed |
| CN-114377565-A | Membranes for removal of metal species from amines | 恩特格里斯公司 | 2022-04-22 | — | — | CN | disclosed |
| WO-2022072466-A1 | MEMBRANES FOR REMOVING METALLIC SPECIES FROM AMINES | ENTEGRIS, INC. (US) | 2022-04-07 | — | — | WO | disclosed |
| US-11174245-B2 | Benzimidazole compounds and derivatives as EGFR inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-11-16 | — | — | US | disclosed |
| US-20200377476-A1 | NEW BENZIMIDAZOLE COMPOUNDS AND DERIVATIVES AS EGFR INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-12-03 | — | — | US | disclosed |
| WO-2019162323-A1 | NEW BENZIMIDAZOLE COMPOUNDS AND DERIVATIVES AS EGFR INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-08-29 | — | — | WO | disclosed |
| US-7863310-B2 | Kinase inhibitors | ELI LILLY AND COMPANY (US) | 2011-01-04 | — | — | US | disclosed |
| US-20080227839-A1 | Kinase Inhibitors | ELI LILLY AND COMPANY | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200377476-A1 | NEW BENZIMIDAZOLE COMPOUNDS AND DERIVATIVES AS EGFR INHIBITORS | EGFR, ERBB2, ERBB3 | HTT 4174/4885CYP1A2 1151/4885CYP2D6 544/4885 |
| US-11174245-B2 | Benzimidazole compounds and derivatives as EGFR inhibitors | EGFR, ERBB2, ERBB3 | HTT 3988/4885CYP1A2 1148/4885CYP2D6 611/4885 |
| US-20080227839-A1 | Kinase Inhibitors | ABL1, MAP3K20, MAP3K19 | HTT 4547/4885CYP1A2 3740/4885CYP2D6 2928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.