Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2773406 | 0.88 | PTGDR2 (0.40) | PTGDR2PTGER2 | |
| SCHEMBL12948911 | 0.88 | PTGDR2 (0.41) | PTGDR2MMP1MMP7MMP8MMP12 | |
| SCHEMBL990553 | 0.86 | PTGDR2 (0.46) | PTGDR2PTPN1KMT2ACXCR3 | |
| SCHEMBL990116 | 0.84 | PTPN1 (0.43) | PTGDR2PTPN1PTGER2CXCR3 | |
| SCHEMBL2773728 | 0.79 | PTGDR2 (0.41) | PTGDR2PTGER2KMT2A | |
| SCHEMBL2772337 | 0.79 | PTGDR2 (0.52) | PTGDR2PTPN1PTGER2 | |
| SCHEMBL2773170 | 0.78 | PTGDR2 (0.42) | PTGDR2PTGER2 | |
| SCHEMBL988505 | 0.77 | PTGDR2 (0.52) | PTGDR2KMT2ACXCR3 | |
| SCHEMBL988190 | 0.77 | MLNR (0.42) | PTGDR2PTPN1KMT2AMLNRCXCR3 | |
| SCHEMBL2773759 | 0.77 | PTGDR2 (0.43) | PTGDR2PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011002814-A2 | BIARYL OXYACETIC ACID COMPOUNDS | LIGAND PHARMACEUTICALS INC. (US) | 2011-01-06 | — | — | WO | claimed |