Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.46 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL990116 | 0.91 | PTPN1 (0.43) | PTGDR2CXCR3CA12CA1CA2 | |
| SCHEMBL988505 | 0.91 | PTGDR2 (0.52) | PTGDR2CXCR3CA12CA1CA2 | |
| SCHEMBL988190 | 0.90 | MLNR (0.42) | PTGDR2CXCR3CA12CA1CA2 | |
| SCHEMBL2773216 | 0.87 | PTGDR2 (0.46) | PTGDR2CXCR3KMT2APTPN1 | |
| SCHEMBL12948844 | 0.87 | PTGDR2 (0.47) | PTGDR2CA12CA1CA2CA4 | |
| SCHEMBL989268 | 0.86 | PTGDR2 (0.40) | PTGDR2CXCR3KMT2APTPN1 | |
| SCHEMBL14875212 | 0.84 | MEN1 (0.45) | PTGDR2KMT2A | |
| SCHEMBL2771016 | 0.83 | PTGDR2 (0.52) | PTGDR2CXCR3PTPN1 | |
| SCHEMBL987918 | 0.82 | PTGDR2 (0.50) | PTGDR2CXCR3CA12CA1CA2 | |
| SCHEMBL12948846 | 0.81 | CA12 (0.48) | PTGDR2CA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011002814-A2 | BIARYL OXYACETIC ACID COMPOUNDS | LIGAND PHARMACEUTICALS INC. (US) | 2011-01-06 | — | — | WO | claimed |