Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PMM2 | O15305 | 1/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.43 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | CECR2 | Q9BXF3 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16480488 | 0.84 | PMM2 (0.45) | PMM2MPIPHOSPHO1ALDH1A1KDM4E | |
| SCHEMBL9893047 | 0.83 | MEN1 (0.54) | ALDH1A1KDM4ETSHRSMN1; SMN2PTGER2 | |
| SCHEMBL9893022 | 0.83 | GAA (0.50) | PMM2MPIPHOSPHO1ALDH1A1HPGD | |
| SCHEMBL9106791 | 0.81 | PMM2 (0.44) | PMM2MPIPHOSPHO1ALDH1A1KDM4E | |
| SCHEMBL9106809 | 0.81 | PMM2 (0.44) | PMM2MPIPHOSPHO1ALDH1A1KDM4E | |
| SCHEMBL9891742 | 0.81 | PMM2 (0.43) | PMM2MPIPHOSPHO1ALDH1A1KDM4E | |
| SCHEMBL1937310 | 0.77 | DDB1 (0.41) | ALDH1A1KDM4EPTGER2MEN1KMT2A | |
| SCHEMBL9892975 | 0.75 | PTGER2 (0.44) | SMN1; SMN2PTGER2MEN1KMT2ANPSR1 | |
| SCHEMBL9893103 | 0.73 | NSD2 (0.45) | DRD2 | |
| SCHEMBL9893020 | 0.71 | PTGER2 (0.42) | ALDH1A1SMN1; SMN2PTGER2LMNAMAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | PMM2 3897/4885MPI 2474/4885PHOSPHO1 864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.