Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | FADS1 | O60427 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9892973 | 0.83 | ELANE (0.43) | GRM2KCNA5 | |
| SCHEMBL16480396 | 0.82 | FADS1 (0.48) | NSD2DRD2ALOX5GRM2FADS1 | |
| SCHEMBL1937310 | 0.80 | DDB1 (0.41) | GRM2NOTUM | |
| SCHEMBL9891737 | 0.79 | NSD2 (0.45) | NSD2DRD2ALOX5GRM2FADS1 | |
| SCHEMBL9892975 | 0.78 | PTGER2 (0.44) | ALOX5NOTUM | |
| SCHEMBL6984473 | 0.76 | NOTUM (0.53) | NSD2DRD2ALOX5FADS1DRD3 | |
| SCHEMBL9105102 | 0.76 | NOTUM (0.53) | NSD2DRD2ALOX5FADS1DRD3 | |
| SCHEMBL7123162 | 0.75 | NOTUM (0.46) | NSD2DRD2ALOX5FADS1DRD3 | |
| SCHEMBL7123171 | 0.75 | NOTUM (0.46) | NSD2DRD2ALOX5FADS1DRD3 | |
| SCHEMBL13934209 | 0.74 | AR (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | NSD2 3859/4885DRD2 246/4885ALOX5 898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.