Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16422722 | 0.84 | HDAC1 (0.49) | PER2TDP1PTGER2PTGER3CYP3A4 | |
| SCHEMBL9893157 | 0.84 | PTGER2 (0.42) | PER2PTGER2PTGER3PTGDRMAP4K1 | |
| SCHEMBL16422286 | 0.84 | TDP1 (0.44) | PER2TDP1PTGER2PTGER3CYP3A4 | |
| SCHEMBL16422287 | 0.84 | TDP1 (0.44) | PER2TDP1PTGER2PTGER3CYP3A4 | |
| SCHEMBL16423189 | 0.84 | TDP1 (0.44) | PER2TDP1PTGER2PTGER3CYP3A4 | |
| SCHEMBL16422721 | 0.84 | HDAC1 (0.49) | PER2TDP1PTGER2PTGER3CYP3A4 | |
| SCHEMBL16423061 | 0.84 | HDAC1 (0.49) | PER2TDP1PTGER2PTGER3CYP3A4 | |
| SCHEMBL9892975 | 0.83 | PTGER2 (0.44) | PTGER2PTGER3PTGDRCYP2C9MEN1 | |
| SCHEMBL9892985 | 0.83 | PTGER2 (0.48) | PER2PTGER2PTGER3CNR2PTGDR | |
| SCHEMBL9892976 | 0.81 | PTGER2 (0.41) | PER2PTGER2PTGER3PTGDRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | PER2 1447/4885TDP1 4464/4885PTGER2 186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.