Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 3/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5509172 | 0.85 | AR (0.40) | PTGER2PTGER3CNR2CYP2C8CYP2C9 | |
| SCHEMBL5513575 | 0.85 | AR (0.40) | PTGER2PTGER3CNR2CYP2C8CYP2C9 | |
| SCHEMBL5509169 | 0.85 | AR (0.40) | PTGER2PTGER3CNR2CYP2C8CYP2C9 | |
| SCHEMBL9893023 | 0.83 | PER2 (0.46) | PTGER2PTGER3CNR2CYP2C9ALDH1A1 | |
| SCHEMBL9893157 | 0.80 | PTGER2 (0.42) | PTGER2PTGER3PTGDRMAP4K1PER2 | |
| SCHEMBL16480454 | 0.80 | NPC1 (0.49) | PTGER2PTGER3CNR2CYP2C8CYP2C9 | |
| SCHEMBL9892975 | 0.80 | PTGER2 (0.44) | PTGER2PTGER3CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL11020419 | 0.79 | PTGER2 (0.52) | PTGER2PTGER3CNR2CYP2C8CYP2C9 | |
| SCHEMBL9891747 | 0.78 | CNR2 (0.47) | PTGER2PTGER3CNR2CYP2C8CYP2C9 | |
| SCHEMBL9892976 | 0.78 | PTGER2 (0.41) | PTGER2PTGER3ALDH1A1PTGDRMAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | PTGER2 186/4885PTGER3 200/4885CNR2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.