Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 7/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9103377 | 0.84 | PHGDH (0.41) | PHGDHTDP1KMT2APTGER2PTGER3 | |
| SCHEMBL9103390 | 0.84 | PHGDH (0.41) | PHGDHTDP1KMT2APTGER2PTGER3 | |
| SCHEMBL2572517 | 0.83 | HDAC6 (0.39) | PHGDHTDP1KMT2APTGER2PTGER3 | |
| SCHEMBL9106214 | 0.83 | HDAC6 (0.39) | PHGDHTDP1KMT2APTGER2PTGER3 | |
| SCHEMBL16542478 | 0.75 | PTGER2 (0.40) | PHGDHTDP1KMT2APTGER2PTGER3 | |
| SCHEMBL9108207 | 0.75 | LMNA (0.40) | PHGDHTDP1KMT2APTGER2PTGER3 | |
| SCHEMBL9108218 | 0.75 | LMNA (0.40) | PHGDHTDP1KMT2APTGER2PTGER3 | |
| SCHEMBL9108663 | 0.73 | KMT2A (0.51) | PHGDHTDP1KMT2APTGER2PTGER3 | |
| SCHEMBL9108668 | 0.73 | KMT2A (0.51) | PHGDHTDP1KMT2APTGER2PTGER3 | |
| SCHEMBL9107624 | 0.72 | TDP1 (0.59) | TDP1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | PHGDH 3135/4885TDP1 4464/4885KMT2A 3551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.