Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 12/20 | 0.56 |
| ▸ | MAOA | P21397 | 9/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5637774 | 0.81 | HRH3 (0.56) | MAOBMAOAMEN1KMT2AKDM4C | |
| SCHEMBL1239192 | 0.79 | PDE3B (0.56) | MAOBMAOAMEN1KMT2AALDH1A1 | |
| SCHEMBL9893697 | 0.79 | MAOB (0.51) | CREBBPMAOBMAOAMEN1KMT2A | |
| SCHEMBL4751126 | 0.78 | MAOB (0.78) | CREBBPMAOBMAOAPDE3BPDE3A | |
| SCHEMBL9893543 | 0.77 | MAOB (0.47) | CREBBPMAOBMAOAMEN1KMT2A | |
| SCHEMBL9893429 | 0.76 | MEN1 (0.44) | CREBBPMAOBMAOAMEN1KMT2A | |
| SCHEMBL5637277 | 0.76 | MAOB (0.78) | CREBBPMAOBMAOA | |
| SCHEMBL31557837 | 0.76 | MAOB (0.78) | CREBBPMAOBMAOA | |
| SCHEMBL30645772 | 0.75 | MAOB (0.67) | CREBBPMAOBMAOAALDH1A1SMN1; SMN2 | |
| SCHEMBL11026437 | 0.74 | MAOB (0.58) | CREBBPMAOBMAOAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940889-B2 | Process for producing benzo [b] [1,4] diazepine-2,4-dione compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2015-01-27 | — | — | US | disclosed |
| US-8796447-B2 | Process for producing benzo[B][1,4]diazepine-2,4-dione compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2014-08-05 | — | — | US | disclosed |
| US-20140194621-A1 | PROCESS FOR PRODUCING BENZO [B] [1,4] DIAZEPINE-2, 4-DIONE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2014-07-10 | — | — | US | disclosed |
| EP-2468733-A1 | PROCESS FOR PRODUCING BENZO[B][1,4]DIAZEPINE-2,4-DIONE COMPOUND | Otsuka Pharmaceutical Co., Ltd. (JP) | 2012-06-27 | — | — | EP | disclosed |
| US-20120149899-A1 | PROCESS FOR PRODUCING BENZO[B][1,4]DIAZEPINE-2,4-DIONE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149899-A1 | PROCESS FOR PRODUCING BENZO[B][1,4]DIAZEPINE-2,4-DIONE COMPOUND | KCNH1, KCNB2, KCNJ2 | CREBBP 1804/4885MAOB 287/4885MAOA 660/4885 |
| US-20140194621-A1 | PROCESS FOR PRODUCING BENZO [B] [1,4] DIAZEPINE-2, 4-DIONE COMPOUND | KCNH1, KCNB2, KCNB1 | CREBBP 1388/4885MAOB 252/4885MAOA 727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.