Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 7/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28580878 | 0.83 | HTR2C (0.47) | HTR2CP2RY14ADRA2ADRD1DRD5 | |
| SCHEMBL29844054 | 0.77 | GRIN2B (0.43) | HTR2CP2RY14ADRA2ADRD1DRD5 | |
| SCHEMBL28818450 | 0.75 | ADRA2A (0.49) | HTR2CP2RY14ADRA2ADRD1DRD5 | |
| SCHEMBL29138789 | 0.75 | ADRA2A (0.49) | HTR2CP2RY14ADRA2ADRD1DRD5 | |
| SCHEMBL28818497 | 0.73 | PROKR1 (0.46) | HTR2CP2RY14ADRA2ADRD1DRD5 | |
| SCHEMBL3723936 | 0.72 | F2R (0.63) | TACR1F2R | |
| SCHEMBL9926852 | 0.72 | F2R (0.63) | TACR1F2R | |
| SCHEMBL22688514 | 0.71 | P2RY14 (0.57) | HTR2CP2RY14ADRA2ADRD1DRD5 | |
| SCHEMBL30945131 | 0.71 | TACR1 (0.40) | HTR2CP2RY14ADRA2ADRD1DRD5 | |
| SCHEMBL3968569 | 0.71 | KMT2A (0.38) | HTR2CP2RY14ADRA2ADRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149694-A1 | Substituted piperidines | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149694-A1 | Substituted piperidines | VHL, PIR, PIGO | HTR2C 2089/4885P2RY14 368/4885ADRA2A 164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.