Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5768417 | 0.80 | MAPK14 (1.00) | MAPK14CYP3A4 | |
| SCHEMBL13739747 | 0.76 | MAPK14 (0.93) | MAPK14CYP3A4 | |
| SCHEMBL989365 | 0.74 | MAPK14 (0.68) | MAPK14CYP3A4 | |
| SCHEMBL4838574 | 0.73 | MAPK14 (1.00) | MAPK14CYP3A4 | |
| SCHEMBL989325 | 0.73 | MAPK14 (0.71) | MAPK14CYP3A4 | |
| SCHEMBL989324 | 0.73 | MAPK14 (0.71) | MAPK14CYP3A4 | |
| SCHEMBL4839601 | 0.71 | MAPK14 (1.00) | MAPK14CYP3A4 | |
| SCHEMBL5773494 | 0.70 | MAPK14 (1.00) | MAPK14CYP3A4 | |
| SCHEMBL989210 | 0.70 | MAPK14 (0.51) | MAPK14CYP3A4 | |
| Alcohol SCHEMBL4841776 | 0.70 | MAPK14 (0.92) | MAPK14CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863310-B2 | Kinase inhibitors | ELI LILLY AND COMPANY (US) | 2011-01-04 | — | — | US | disclosed |
| US-20080227839-A1 | Kinase Inhibitors | ELI LILLY AND COMPANY | 2008-09-18 | — | — | US | disclosed |
| EP-1720862-A1 | KINASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005080380-A1 | KINASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2005-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227839-A1 | Kinase Inhibitors | ABL1, MAP3K20, MAP3K19 | MAPK14 341/4885CYP3A4 3973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.